347. Zhang X, Perica T, Teichmann SA. Evolution of protein structures and interactions from the perspective of residue contact networks. Curr Opin Struct Biol. 2013 Jul 25. [PubMed]
346. Hall Z, Hernández H, Marsh JA, Teichmann SA, Robinson CV. The Role of Salt Bridges, Charge Density, and Subunit Flexibility in Determining Disassembly Routes of Protein Complexes. Structure. 2013 Jul 9. [PubMed]
345. Marcotte E, Boone C, Babu MM, Gavin AC. Network Biology editorial 2013. Mol Biosyst. 2013 Jul;9(7):1557-8. [PubMed]
344. Roberts EW, Deonarine A, Jones JO, Denton AE, Feig C, Lyons SK, Espeli M, et al. Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia. J Exp Med. 2013 Jun 3;210(6):1137-51. [PubMed]
343. Buljan M, Chalancon G, Dunker AK, Bateman A, Balaji S, Fuxreiter M, Babu MM. Alternative splicing of intrinsically disordered regions and rewiring of protein interactions. Curr Opin Struct Biol. 2013 Jun;23(3):443-50. [PubMed]
342. Thanga Viji V, Deepa K, Velmurugan S, Donio MB, Adlin Jenifer J, Babu MM, Citarasu T. Vaccination strategies to protect goldfish Carassius auratus against Aeromonas hydrophila infection. Dis Aquat Organ. 2013 Apr 29;104(1):45-57. [PubMed]
341. Levy ED, Teichmann S. Structural, evolutionary, and assembly principles of protein oligomerization. Prog Mol Biol Transl Sci. 2013;117:25-51. [PubMed]
340. Campiteli MG, Comin CH, Costa Lda F, Babu MM, Cesar RM. A methodology to infer gene networks from spatial patterns of expression--an application to fluorescence in situ hybridization images. Mol Biosyst. 2013 Jul;9(7):1926-30. [PubMed]
339. Marsh JA, Hernández H, Hall Z, Ahnert SE, Perica T, Robinson CV, Teichmann SA. Protein complexes are under evolutionary selection to assemble via ordered pathways. Cell. 2013 Apr 11;153(2):461-70. [PubMed]
338. Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM. Molecular signatures of G-protein-coupled receptors. Nature. 2013 Feb 14;494(7436):185-94. Review. [PubMed]
337. Nishi H, Fong JH, Chang C, Teichmann SA, Panchenko AR. Regulation of protein-protein binding by coupling between phosphorylation and intrinsic disorder: analysis of human protein complexes. Mol Biosyst. 2013 Jul;9(7):1620-6. [PubMed]
336. Lewis TE, Sillitoe I, Andreeva A, Blundell TL, Buchan DW, Chothia C, Cuff A, et al. Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains. Nucleic Acids Res. 2013 Jan 1;41(D1):D499-D507. [PubMed] [PDF]
335. Levy ED, De S, Teichmann SA. Cellular crowding imposes global constraints on the chemistry and evolution of proteomes. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20461-6. [PubMed] [PDF]
334. Kruse K, Sewitz S, Babu MM. A complex network framework for unbiased statistical analyses of DNA-DNA contact maps. Nucleic Acids Res. 2013 Jan 1;41(2):701-10. [PubMed] [PDF]
333. Gsponer J, Babu MM. Cellular strategies for regulating functional and nonfunctional protein aggregation. Cell Rep. 2012 Nov 29;2(5):1425-37. [PubMed]
332. Teichmann SA, Wigge PA, Charoensawan V. Uncovering the interplay between DNA sequence preferences of transcription factors and nucleosomes. Cell Cycle. 2012 Dec 15;11(24):4487-8. [PubMed] [PDF]
331. Marsh JA, Teichmann SA, Forman-Kay JD. Probing the diverse landscape of protein flexibility and binding. Curr Opin Struct Biol. 2012 Sep 19. [PubMed]
330. Babu MM, Kriwacki RW, Pappu RV. Structural biology. Versatility from protein disorder. Science. 2012 Sep 21;337(6101):1460-1. [PubMed]
329. Sanchez de Groot N, Torrent M, Villar-Piqué A, Lang B, Ventura S, Gsponer J, Babu MM. Evolutionary selection for protein aggregation. Biochem Soc Trans. 2012 Oct 1;40(5):1032-7. [PubMed]
328. Charoensawan V, Janga SC, Bulyk ML, Babu MM, Teichmann SA. DNA sequence preferences of transcriptional activators correlate more strongly than repressors with nucleosomes. Mol Cell. 2012 Jul 27;47(2):183-92. [PubMed]
327. Chandra T, Kirschner K, Thuret JY, Pope BD, Ryba T, Newman S, Ahmed K, et al. Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation. Mol Cell. 2012 Jul 10. [PubMed]
326. Buljan M, Chalancon G, Eustermann S, Wagner GP, Fuxreiter M, Bateman A, Babu MM. Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks. Mol Cell. 2012 Jun 29;46(6):871-83. [PubMed]
325. Flock T, Venkatakrishnan A, Vinothkumar K, Babu MM. Deciphering membrane protein structures from protein sequences. Genome Biol. 2012 Jun 27;13(6):160. [PubMed]
324. Perica T, Marsh JA, Sousa FL, Natan E, Colwell LJ, Ahnert SE, Teichmann SA. The emergence of protein complexes: quaternary structure, dynamics and allostery. Colworth Medal Lecture. Biochem Soc Trans. 2012 Jun 1;40(3):475-91. [PubMed]
323. Perica T, Chothia C, Teichmann SA. Evolution of oligomeric state through geometric coupling of protein interfaces. Proc Natl Acad Sci U S A. 2012 May 7. [PubMed] [PDF]
322. Liberles DA, Teichmann SA, Bahar I, Bastolla U, Bloom J, Bornberg-Bauer E, Colwell LJ, et al. The interface of protein structure, protein biophysics, and molecular evolution. Protein Sci. 2012 Mar 30. [PubMed]
321. Hebenstreit D, Deonarine A, Babu MM, Teichmann SA. Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells. Curr Opin Cell Biol. 2012 Apr 10. [PubMed]
320. Yogeeswaran A, Velmurugan S, Punitha SM, Babu MM, Selvaraj T, Kumaran T, Citarasu T. Protection of Penaeus monodon against white spot syndrome virus by inactivated vaccine with herbal immunostimulants. Fish Shellfish Immunol. 2012 Jun;32(6):1058-67. [PubMed]
319. Nagulapalli M, Parigi G, Yuan J, Gsponer J, Deraos G, Bamm VV, Harauz G, et al. Recognition pliability is coupled to structural heterogeneity: a calmodulin intrinsically disordered binding region complex. Structure. 2012 Mar 7;20(3):522-33. [PubMed]
318. Chalancon G, Kruse K, Babu MM. Cell biology. Reconfiguring regulation. Science. 2012 Mar 2;335(6072):1050-1. [PubMed]
317. Chalancon G, Ravarani CN, Balaji S, Martinez-Arias A, Aravind L, Jothi R, Babu MM. Interplay between gene expression noise and regulatory network architecture. Trends Genet. 2012 May;28(5):221-32. [PubMed]
316. Brookes E, de Santiago I, Hebenstreit D, Morris KJ, Carroll T, Xie SQ, Stock JK, et al. Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell. 2012 Feb 3;10(2):157-70. [PubMed]
315. Trott J, Hayashi K, Surani A, Babu MM, Martinez-Arias A. Dissecting ensemble networks in ES cell populations reveals micro-heterogeneity underlying pluripotency. Mol Biosyst. 2012 Jan 5. [PubMed]
314. Moeller A, Xie SQ, Hosp F, Lang B, Phatnani HP, James S, Ramirez F, et al. Proteomic analysis of mitotic RNA polymerase IIreveals novel interactors and association withproteins dysfunctional in disease. Mol Cell Proteomics. 2011 Dec 22. [PubMed] [PDF]
313. Babu MM. Intrinsically disordered proteins. Mol Biosyst. 2012 Jan 1;8(1):21. [PubMed]
312. Escudero LM, da F Costa L, Kicheva A, Briscoe J, Freeman M, Babu MM. Epithelial organisation revealed by a network of cellular contacts. Nat Commun. 2011 Nov 8;2:526. [PubMed]
311. Vaquerizas JM, Teichmann SA, Luscombe NM. How do you find transcription factors? Computational approaches to compile and annotate repertoires of regulators for any genome. Methods Mol Biol. 2012;786:3-19. [PubMed]
310. Shetty NS, Vallabhaneni S, Patil A, Babu MM, Baig A. Unreported location and presentation for a parasitic ovarian dermoid cyst in an indirect inguinal hernia. Hernia. 2011 Sep 9. [PubMed]
309. Chavali S, Morais DA, Gough J, Babu MM. Evolution of eukaryotic genome architecture: Insights from the study of a rapidly evolving metazoan, Oikopleura dioica: Non-adaptive forces such as elevated mutation rates may influence the evolution of genome architecture. Bioessays. 2011 Aug;33(8):592-601. Review. [PubMed]
308. Hebenstreit D, Fang M, Gu M, Charoensawan V, van Oudenaarden A, Teichmann SA. RNA sequencing reveals two major classes of gene expression levels in metazoan cells. Mol Syst Biol. 2011 Jun 7;7:497. [PubMed] [PDF]
307. Marsh JA, Teichmann SA. Relative solvent accessible surface area predicts protein conformational changes upon binding. Structure. 2011 Jun 8;19(6):859-67. [PubMed]
306. Hebenstreit D, Teichmann SA. Analysis and simulation of gene expression profiles in pure and mixed cell populations. Phys Biol. 2011 Jun;8(3):035013. [PubMed]
305. Babu MM, van der Lee R, de Groot NS, Gsponer J. Intrinsically disordered proteins: regulation and disease. Curr Opin Struct Biol. 2011 Jun;21(3):432-40. Review. [PubMed]
304. Sucgang R, Kuo A, Tian X, Salerno W, Parikh A, Feasley CL, Dalin E, et al. Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum. Genome Biol. 2011;12(2):R20. [PubMed]
303. Rossmann M, Sukumaran M, Penn AC, Veprintsev DB, Babu MM, Greger IH. Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers. EMBO J. 2011 Mar 2;30(5):959-71. [PubMed]
302. Kapitzky L, Beltrao P, Berens TJ, Gassner N, Zhou C, Wüster A, Wu J, et al. Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol. 2010 Dec 21;6:451. [PubMed] [PDF]
301. Su J, Teichmann SA, Down TA. Assessing computational methods of cis-regulatory module prediction. PLoS Comput Biol. 2010 Dec 2;6(12):e1001020. [PubMed] [PDF]
300. Hebenstreit D, Gu M, Haider S, Turner DJ, Liò P, Teichmann SA. EpiChIP: gene-by-gene quantification of epigenetic modification levels. Nucleic Acids Res. 2011 Mar;39(5):e27. [PubMed] [PDF]
299. Mittal R, Sukumaran SK, Selvaraj SK, Wooster DG, Babu MM, Schreiber AD, Verbeek JS, et al. Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1. PLoS Pathog. 2010 Nov 18;6(11):e1001203. [PubMed] [PDF]
298. Weber KP, De S, Kozarewa I, Turner DJ, Babu MM, de Bono M. Whole genome sequencing highlights genetic changes associated with laboratory domestication of C. elegans. PLoS One. 2010 Nov 11;5(11):e13922. [PubMed] [PDF]
297. de Lima Morais DA, Fang H, Rackham OJ, Wilson D, Pethica R, Chothia C, Gough J. SUPERFAMILY 1.75 including a domain-centric gene ontology method. Nucleic Acids Res. 2011 Jan;39(Database issue):D427-34. [PubMed] [PDF]
296. Charoensawan V, Adryan B, Martin S, Söllner C, Thisse B, Thisse C, Wright GJ, et al. The impact of gene expression regulation on evolution of extracellular signaling pathways. Mol Cell Proteomics. 2010 Dec;9(12):2666-77. [PubMed]
295. Wuster A, Venkatakrishnan AJ, Schertler GF, Babu MM. Spial: analysis of subtype-specific features in multiple sequence alignments of proteins. Bioinformatics. 2010 Nov 15;26(22):2906-7. [PubMed] [PDF]
294. Babu MM. Early Career Research Award Lecture. Structure, evolution and dynamics of transcriptional regulatory networks. Biochem Soc Trans. 2010 Oct;38(5):1155-78. [PubMed]
293. Chalancon G, Babu MM. Nanobiotechnology: Scaling up synthetic gene circuits. Nat Nanotechnol. 2010 Sep;5(9):631-3. [PubMed]
292. Martin S, Söllner C, Charoensawan V, Adryan B, Thisse B, Thisse C, Teichmann S, et al. Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling. Mol Cell Proteomics. 2010 Dec;9(12):2654-65. [PubMed] [PDF]
291. Immanuel G, Uma RP, Iyapparaj P, Citarasu T, Peter SM, Babu MM, Palavesam A. Dietary medicinal plant extracts improve growth, immune activity and survival of tilapia Oreochromis mossambicus. J Fish Biol. 2009 May;74(7):1462-75. [PubMed]
290. Charoensawan V, Wilson D, Teichmann SA. Genomic repertoires of DNA-binding transcription factors across the tree of life. Nucleic Acids Res. 2010 Nov;38(21):7364-77. Review. [PubMed] [PDF]
289. Charoensawan V, Wilson D, Teichmann SA. Lineage-specific expansion of DNA-binding transcription factor families. Trends Genet. 2010 Sep;26(9):388-93. [PubMed]
288. Venkatakrishnan AJ, Levy ED, Teichmann SA. Homomeric protein complexes: evolution and assembly. Biochem Soc Trans. 2010 Aug;38(4):879-82. Review. [PubMed]
287. Charoensawan V, Wilson D, Teichmann SA. Genomic repertoires of DNA-binding transcription factors across the tree of life. Nucleic Acids Res. 2010 Nov;38(21):7364-77. Review. [PubMed] [PDF]
286. Charoensawan V, Wilson D, Teichmann SA. Lineage-specific expansion of DNA-binding transcription factor families. Trends Genet. 2010 Sep;26(9):388-93. [PubMed]
285. Marsh JA, Teichmann SA. How do proteins gain new domains? Genome Biol. 2010;11(7):126. [PubMed]
284. De S, Babu MM. A time-invariant principle of genome evolution. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13004-9. [PubMed] [PDF]
283. Levy ED, Teichmann SA. Systemizing the structures and structuring the system. Expert Rev Proteomics. 2010 Jun;7(3):319-22. [PubMed]
282. De S, Babu MM. Genomic neighbourhood and the regulation of gene expression. Curr Opin Cell Biol. 2010 Jun;22(3):326-33. Review. [PubMed]
281. Teichmann SA, Grishin N. Sequences and topology: evolution of proteins and evolution of computational approaches. Curr Opin Struct Biol. 2010 Jun;20(3):333-4. [PubMed]
280. Perica T, Chothia C. Ubiquitin--molecular mechanisms for recognition of different structures. Curr Opin Struct Biol. 2010 Jun;20(3):367-76. Review. [PubMed]
279. Adryan B, Teichmann SA. The developmental expression dynamics of Drosophila melanogaster transcription factors. Genome Biol. 2010;11(4):R40. [PubMed] [PDF]
278. Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu MM, Choudhary J. An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Cell Stem Cell. 2010 Apr 2;6(4):382-95. [PubMed] [PDF]
277. Shruthi H, Babu MM, Sankaran K. TAT-pathway-dependent lipoproteins as a niche-based adaptation in prokaryotes. J Mol Evol. 2010 Apr;70(4):359-70. [PubMed]
276. Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell. 2010 Mar 5;140(5):744-52. [PubMed]
275. Pérez-Rueda E, Janga SC. Identification and genomic analysis of transcription factors in archaeal genomes exemplifies their functional architecture and evolutionary origin. Mol Biol Evol. 2010 Jun;27(6):1449-59. [PubMed] [PDF]
274. Wuster A, Babu MM. Transcriptional control of the quorum sensing response in yeast. Mol Biosyst. 2010 Jan;6(1):134-41. [PubMed]
273. Babu MM, Mori H. Computational and systems biology. Mol Biosyst. 2009 Dec;5(12):1391. [PubMed]
272. Mittal N, Roy N, Babu MM, Janga SC. Dissecting the expression dynamics of RNA-binding proteins in posttranscriptional regulatory networks. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20300-5. [PubMed] [PDF]
271. Pfreundt U, James DP, Tweedie S, Wilson D, Teichmann SA, Adryan B. FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database. Nucleic Acids Res. 2010 Jan;38(Database issue):D443-7. [PubMed] [PDF]
270. Pérez-Rueda E, Janga SC, Martínez-Antonio A. Scaling relationship in the gene content of transcriptional machinery in bacteria. Mol Biosyst. 2009 Dec;5(12):1494-501. Review. [PubMed]
269. Janga SC, Tzakos A. Structure and organization of drug-target networks: insights from genomic approaches for drug discovery. Mol Biosyst. 2009 Dec;5(12):1536-48. Review. [PubMed]
268. Zhang XY, Langenick J, Traynor D, Babu MM, Kay RR, Patel KJ. Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum. PLoS Genet. 2009 Sep;5(9):e1000645. [PubMed] [PDF]
267. Mittal N, Babu MM, Roy N. The efficiency of mitochondrial electron transport chain is increased in the long-lived mrg19 Saccharomyces cerevisiae. Aging Cell. 2009 Dec;8(6):643-53. [PubMed]
266. Jothi R, Balaji S, Wuster A, Grochow JA, Gsponer J, Przytycka TM, Aravind L, et al. Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture. Mol Syst Biol. 2009;5:294. [PubMed] [PDF]
265. Janga SC, Pérez-Rueda E. Plasticity of transcriptional machinery in bacteria is increased by the repertoire of regulatory families. Comput Biol Chem. 2009 Aug;33(4):261-8. [PubMed]
264. Pache RA, Babu MM, Aloy P. Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions. BMC Syst Biol. 2009 Jul 18;3:74. [PubMed] [PDF]
263. Janky R, Helden J, Babu MM. Investigating transcriptional regulation: from analysis of complex networks to discovery of cis-regulatory elements. Methods. 2009 Jul;48(3):277-86. [PubMed]
262. Babu MM, Lang B, Aravind L. Methods to reconstruct and compare transcriptional regulatory networks. Methods Mol Biol. 2009;541:163-80. Review. [PubMed]
261. FANTOM Consortium, Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet. 2009 May;41(5):553-62. [PubMed]
260. Wilson NK, Miranda-Saavedra D, Kinston S, Bonadies N, Foster SD, Calero-Nieto F, Dawson MA, et al. The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development. Blood. 2009 May 28;113(22):5456-65. [PubMed] [PDF]
259. Gsponer J, Babu MM. The rules of disorder or why disorder rules. Prog Biophys Mol Biol. 2009 Feb-Apr;99(2-3):94-103. Review. [PubMed]
258. Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM. A census of human transcription factors: function, expression and evolution. Nat Rev Genet. 2009 Apr;10(4):252-63. [PubMed] [PDF]
257. Chothia C, Gough J. Genomic and structural aspects of protein evolution. Biochem J. 2009 Apr 1;419(1):15-28. Review. [PubMed] [PDF]
256. De S, Teichmann SA, Babu MM. The impact of genomic neighborhood on the evolution of human and chimpanzee transcriptome. Genome Res. 2009 May;19(5):785-94. [PubMed] [PDF]
255. Watkins NA, Gusnanto A, de Bono B, De S, Miranda-Saavedra D, Hardie DL, Angenent WG, et al. A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood. 2009 May 7;113(19):e1-9. [PubMed] [PDF]
254. Kummerfeld SK, Teichmann SA. Protein domain organisation: adding order. BMC Bioinformatics. 2009 Jan 29;10:39. [PubMed] [PDF]
253. Janga SC, Babu MM. Transcript stability in the protein interaction network of Escherichia coli. Mol Biosyst. 2009 Feb;5(2):154-62. [PubMed]
252. Alpi AF, Pace PE, Babu MM, Patel KJ. Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Mol Cell. 2008 Dec 26;32(6):767-77. [PubMed]
251. Teichmann S, Patel NH. Genomes and evolution: multidimensional approaches to understanding diversity. Curr Opin Genet Dev. 2008 Dec;18(6):469-71. [PubMed]
250. Janga SC, Babu MM. Network-based approaches for linking metabolism with environment. Genome Biol. 2008;9(11):239. Review. [PubMed] [PDF]
249. Gsponer J, Futschik ME, Teichmann SA, Babu MM. Tight regulation of unstructured proteins: from transcript synthesis to protein degradation. Science. 2008 Nov 28;322(5906):1365-8. [PubMed] [PDF]
248. Wilson D, Pethica R, Zhou Y, Talbot C, Vogel C, Madera M, Chothia C, et al. SUPERFAMILY--sophisticated comparative genomics, data mining, visualization and phylogeny. Nucleic Acids Res. 2009 Jan;37(Database issue):D380-6. [PubMed] [PDF]
247. Babu MM, Janga SC, de Santiago I, Pombo A. Eukaryotic gene regulation in three dimensions and its impact on genome evolution. Curr Opin Genet Dev. 2008 Dec;18(6):571-82. [PubMed]
246. Miranda-Saavedra D, De S, Trotter MW, Teichmann SA, Göttgens B. BloodExpress: a database of gene expression in mouse haematopoiesis. Nucleic Acids Res. 2009 Jan;37(Database issue):D873-9. [PubMed] [PDF]
245. Ahnert SE, Teichmann SA. Networks for all. Genome Biol. 2008 Oct 27;9(10):324. [PubMed] [PDF]
244. Janga SC, Collado-Vides J, Babu MM. Transcriptional regulation constrains the organization of genes on eukaryotic chromosomes. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15761-6. [PubMed] [PDF]
243. De S, Lopez-Bigas N, Teichmann SA. Patterns of evolutionary constraints on genes in humans. BMC Evol Biol. 2008 Oct 7;8:275. [PubMed] [PDF]
242. Seshasayee AS, Fraser GM, Babu MM, Luscombe NM. Principles of transcriptional regulation and evolution of the metabolic system in E. coli. Genome Res. 2009 Jan;19(1):79-91. [PubMed] [PDF]
241. Adryan B, Teichmann SA. Computational identification of site-specific transcription factors in Drosophila. Fly (Austin). 2007 May-Jun;1(3):142-5. [PubMed] [PDF]
240. Madan Babu M, Balaji S, Aravind L. General trends in the evolution of prokaryotic transcriptional regulatory networks. Genome Dyn. 2007;3:66-80. Review. [PubMed] [PDF]
239. Bui JM, Cavalli A, Gsponer J. Identification of aggregation-prone elements by using interaction-energy matrices. Angew Chem Int Ed Engl. 2008;47(38):7267-9. [PubMed]
238. Babu MM. Computational approaches to study transcriptional regulation. Biochem Soc Trans. 2008 Aug;36(Pt 4):758-65. Review. [PubMed]
237. Levy ED, Boeri Erba E, Robinson CV, Teichmann SA. Assembly reflects evolution of protein complexes. Nature. 2008 Jun 26;453(7199):1262-5. [PubMed] [PDF]
236. Dhulesia A, Gsponer J, Vendruscolo M. Mapping of two networks of residues that exhibit structural and dynamical changes upon binding in a PDZ domain protein. J Am Chem Soc. 2008 Jul 16;130(28):8931-9. [PubMed] [PDF]
235. Teichmann SA, Grishin NV. Sequences and topology: from genome structure to protein structure. Curr Opin Struct Biol. 2008 Jun;18(3):340-1. [PubMed]
234. Balaji S, Iyer LM, Babu MM, Aravind L. Comparison of transcription regulatory interactions inferred from high-throughput methods: what do they reveal? Trends Genet. 2008 Jul;24(7):319-23. [PubMed]
233. Gsponer J, Christodoulou J, Cavalli A, Bui JM, Richter B, Dobson CM, Vendruscolo M. A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction. Structure. 2008 May;16(5):736-46. [PubMed]
232. Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet. 2008 Jun;40(6):768-75. [PubMed] [PDF]
231. Bemporad F, Gsponer J, Hopearuoho HI, Plakoutsi G, Stati G, Stefani M, Taddei N, et al. Biological function in a non-native partially folded state of a protein. EMBO J. 2008 May 21;27(10):1525-35. [PubMed] [PDF]
230. Hermsen R, ten Wolde PR, Teichmann S. Chance and necessity in chromosomal gene distributions. Trends Genet. 2008 May;24(5):216-9. Review. [PubMed]
229. Pollock RF, Adryan B. BioSAVE: display of scored annotation within a sequence context. BMC Bioinformatics. 2008 Mar 20;9:157. [PubMed] [PDF]
228. Wuster A, Madan Babu M. Chemogenomics and biotechnology. Trends Biotechnol. 2008 May;26(5):252-8. Review. [PubMed]
227. Lopez-Bigas N, De S, Teichmann SA. Functional protein divergence in the evolution of Homo sapiens. Genome Biol. 2008;9(2):R33. [PubMed] [PDF]
226. Wilson D, Charoensawan V, Kummerfeld SK, Teichmann SA. DBD--taxonomically broad transcription factor predictions: new content and functionality. Nucleic Acids Res. 2008 Jan;36(Database issue):D88-92. [PubMed] [PDF]
225. Andreeva A, Howorth D, Chandonia JM, Brenner SE, Hubbard TJ, Chothia C, Murzin AG. Data growth and its impact on the SCOP database: new developments. Nucleic Acids Res. 2008 Jan;36(Database issue):D419-25. [PubMed] [PDF]
224. Drosophila 12 Genomes Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, et al. Evolution of genes and genomes on the Drosophila phylogeny. Nature. 2007 Nov 8;450(7167):203-18. [PubMed] [PDF]
223. Olesen LE, Ford MG, Schmid EM, Vallis Y, Babu MM, Li PH, Mills IG, et al. Solitary and repetitive binding motifs for the AP2 complex alpha-appendage in amphiphysin and other accessory proteins. J Biol Chem. 2008 Feb 22;283(8):5099-109. [PubMed] [PDF]
222. Wuster A, Babu MM. Conservation and evolutionary dynamics of the agr cell-to-cell communication system across firmicutes. J Bacteriol. 2008 Jan;190(2):743-6. [PubMed] [PDF]
221. Lang B, Blot N, Bouffartigues E, Buckle M, Geertz M, Gualerzi CO, Mavathur R, et al. High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes. Nucleic Acids Res. 2007;35(18):6330-7. [PubMed] [PDF]
220. Massie CE, Adryan B, Barbosa-Morais NL, Lynch AG, Tran MG, Neal DE, Mills IG. New androgen receptor genomic targets show an interaction with the ETS1 transcription factor. EMBO Rep. 2007 Sep;8(9):871-8. [PubMed]
219. Balaji S, Babu MM, Aravind L. Interplay between network structures, regulatory modes and sensing mechanisms of transcription factors in the transcriptional regulatory network of E. coli. J Mol Biol. 2007 Sep 28;372(4):1108-22. [PubMed]
218. Adryan B, Woerfel G, Birch-Machin I, Gao S, Quick M, Meadows L, Russell S, et al. Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila. Genome Biol. 2007;8(8):R167. [PubMed] [PDF]
217. Audit B, Levy ED, Gilks WR, Goldovsky L, Ouzounis CA. CORRIE: enzyme sequence annotation with confidence estimates. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S3. [PubMed] [PDF]
216. Holohan EE, Kwong C, Adryan B, Bartkuhn M, Herold M, Renkawitz R, Russell S, et al. CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex. PLoS Genet. 2007 Jul;3(7):e112. [PubMed] [PDF]
215. Sasidharan R, Chothia C. The selection of acceptable protein mutations. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10080-5. [PubMed] [PDF]
214. Anbarasu A, Anand S, Babu MM, Sethumadhavan R. Investigations on C-H...pi interactions in RNA binding proteins. Int J Biol Macromol. 2007 Aug 1;41(3):251-9. [PubMed]
213. Pereira-Leal JB, Levy ED, Kamp C, Teichmann SA. Evolution of protein complexes by duplication of homomeric interactions. Genome Biol. 2007;8(4):R51. [PubMed] [PDF]
212. Han JH, Batey S, Nickson AA, Teichmann SA, Clarke J. The folding and evolution of multidomain proteins. Nat Rev Mol Cell Biol. 2007 Apr;8(4):319-30. Review. [PubMed] [PDF]
211. Talavera D, Vogel C, Orozco M, Teichmann SA, de la Cruz X. The (in)dependence of alternative splicing and gene duplication. PLoS Comput Biol. 2007 Mar 2;3(3):e33. [PubMed] [PDF]
210. Richter B, Gsponer J, Várnai P, Salvatella X, Vendruscolo M. The MUMO (minimal under-restraining minimal over-restraining) method for the determination of native state ensembles of proteins. J Biomol NMR. 2007 Feb;37(2):117-35. [PubMed] [PDF]
209. Bashton M, Chothia C. The generation of new protein functions by the combination of domains. Structure. 2007 Jan;15(1):85-99. [PubMed] [PDF]
208. Babu MM, Iyer LM, Balaji S, Aravind L. The natural history of the WRKY-GCM1 zinc fingers and the relationship between transcription factors and transposons. Nucleic Acids Res. 2006;34(22):6505-20. [PubMed] [PDF]
207. Gsponer J, Hopearuoho H, Cavalli A, Dobson CM, Vendruscolo M. Geometry, energetics, and dynamics of hydrogen bonds in proteins: structural information derived from NMR scalar couplings. J Am Chem Soc. 2006 Nov 29;128(47):15127-35. [PubMed] [PDF]
206. Levy ED, Pereira-Leal JB, Chothia C, Teichmann SA. 3D complex: a structural classification of protein complexes. PLoS Comput Biol. 2006 Nov 17;2(11):e155. [PubMed] [PDF]
205. Babu MM, Balaji S, Iyer LM, Aravind L. Estimating the prevalence and regulatory potential of the telomere looping effect in yeast transcription regulation. Cell Cycle. 2006 Oct;5(20):2354-63. [PubMed] [PDF]
204. Wilson D, Madera M, Vogel C, Chothia C, Gough J. The SUPERFAMILY database in 2007: families and functions. Nucleic Acids Res. 2007 Jan;35(Database issue):D308-13. [PubMed] [PDF]
203. Stahl M, Schuh R, Adryan B. Identification of FGF-dependent genes in the Drosophila tracheal system. Gene Expr Patterns. 2007 Jan;7(1-2):202-9. [PubMed]
202. Chakkaravarthi S, Babu MM, Gromiha MM, Jayaraman G, Sethumadhavan R. Exploring the environmental preference of weak interactions in (alpha/beta)8 barrel proteins. Proteins. 2006 Oct 1;65(1):75-86. [PubMed]
201. Balaji S, Babu MM, Iyer LM, Luscombe NM, Aravind L. Comprehensive analysis of combinatorial regulation using the transcriptional regulatory network of yeast. J Mol Biol. 2006 Jun 30;360(1):213-27. [PubMed]
200. Vogel C, Chothia C. Protein family expansions and biological complexity. PLoS Comput Biol. 2006 May;2(5):e48. [PubMed] [PDF]
199. Balaji S, Iyer LM, Aravind L, Babu MM. Uncovering a hidden distributed architecture behind scale-free transcriptional regulatory networks. J Mol Biol. 2006 Jun 30;360(1):204-12. [PubMed]
198. Han JH, Kerrison N, Chothia C, Teichmann SA. Divergence of interdomain geometry in two-domain proteins. Structure. 2006 May;14(5):935-45. [PubMed] [PDF]
197. Nye TM, Berzuini C, Gilks WR, Babu MM, Teichmann S. Predicting the strongest domain-domain contact in interacting protein pairs. Stat Appl Genet Mol Biol. 2006;5:Article5. [PubMed] [PDF]
196. Iyer LM, Babu MM, Aravind L. The HIRAN domain and recruitment of chromatin remodeling and repair activities to damaged DNA. Cell Cycle. 2006 Apr;5(7):775-82. [PubMed] [PDF]
195. Adryan B, Teichmann SA. FlyTF: a systematic review of site-specific transcription factors in the fruit fly Drosophila melanogaster. Bioinformatics. 2006 Jun 15;22(12):1532-3. [PubMed] [PDF]
194. Babu MM, Priya ML, Selvan AT, Madera M, Gough J, Aravind L, Sankaran K. A database of bacterial lipoproteins (DOLOP) with functional assignments to predicted lipoproteins. J Bacteriol. 2006 Apr;188(8):2761-73. [PubMed] [PDF]
193. Madan Babu M, Teichmann SA, Aravind L. Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J Mol Biol. 2006 Apr 28;358(2):614-33. [PubMed]
192. Pereira-Leal JB, Levy ED, Teichmann SA. The origins and evolution of functional modules: lessons from protein complexes. Philos Trans R Soc Lond B Biol Sci. 2006 Mar 29;361(1467):507-17. Review. [PubMed]
191. Kummerfeld SK, Teichmann SA. DBD: a transcription factor prediction database. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D74-81. [PubMed] [PDF]
190. Babu MM, Aravind L. Adaptive evolution by optimizing expression levels in different environments. Trends Microbiol. 2006 Jan;14(1):11-4. [PubMed]
189. Wright CF, Teichmann SA, Clarke J, Dobson CM. The importance of sequence diversity in the aggregation and evolution of proteins. Nature. 2005 Dec 8;438(7069):878-81. [PubMed] [PDF]
188. Teichmann SA, Bornberg-Bauer E, Luscombe NM. Transcriptional networking. Genome Biol. 2005;6(9):344. [PubMed] [PDF]
187. Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, et al. The transcriptional landscape of the mammalian genome. Science. 2005 Sep 2;309(5740):1559-63. [PubMed] [PDF]
186. Balaji S, Babu MM, Iyer LM, Aravind L. Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains. Nucleic Acids Res. 2005 Jul 21;33(13):3994-4006. [PubMed] [PDF]
185. Eichinger L, Pachebat JA, Glöckner G, Rajandream MA, Sucgang R, Berriman M, Song J, et al. The genome of the social amoeba Dictyostelium discoideum. Nature. 2005 May 5;435(7038):43-57. [PubMed] [PDF]
184. Aravind L, Anantharaman V, Balaji S, Babu MM, Iyer LM. The many faces of the helix-turn-helix domain: transcription regulation and beyond. FEMS Microbiol Rev. 2005 Apr;29(2):231-62. Review. [PubMed]
183. Pereira-Leal JB, Teichmann SA. Novel specificities emerge by stepwise duplication of functional modules. Genome Res. 2005 Apr;15(4):552-9. [PubMed] [PDF]
182. Kunin V, Teichmann SA, Huynen MA, Ouzounis CA. The properties of protein family space depend on experimental design. Bioinformatics. 2005 Jun 1;21(11):2618-22. [PubMed] [PDF]
181. Bornberg-Bauer E, Beaussart F, Kummerfeld SK, Teichmann SA, Weiner J 3rd. The evolution of domain arrangements in proteins and interaction networks. Cell Mol Life Sci. 2005 Feb;62(4):435-45. Review. [PubMed] [PDF]
180. Kummerfeld SK, Teichmann SA. Relative rates of gene fusion and fission in multi-domain proteins. Trends Genet. 2005 Jan;21(1):25-30. [PubMed]
179. Vogel C, Teichmann SA, Pereira-Leal J. The relationship between domain duplication and recombination. J Mol Biol. 2005 Feb 11;346(1):355-65. [PubMed]
178. Nye TM, Berzuini C, Gilks WR, Babu MM, Teichmann SA. Statistical analysis of domains in interacting protein pairs. Bioinformatics. 2005 Apr 1;21(7):993-1001. [PubMed] [PDF]
177. Praefcke GJ, Ford MG, Schmid EM, Olesen LE, Gallop JL, Peak-Chew SY, Vallis Y, et al. Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis. EMBO J. 2004 Nov 10;23(22):4371-83. [PubMed] [PDF]
176. Luscombe NM, Babu MM. GenCompass: a universal system for analysing gene expression for any genome. Trends Biotechnol. 2004 Nov;22(11):552-5. [PubMed]
175. Luscombe NM, Babu MM, Yu H, Snyder M, Teichmann SA, Gerstein M. Genomic analysis of regulatory network dynamics reveals large topological changes. Nature. 2004 Sep 16;431(7006):308-12. [PubMed] [PDF]
174. Teichmann SA, Veitia RA. Genes encoding subunits of stable complexes are clustered on the yeast chromosomes: an interpretation from a dosage balance perspective. Genetics. 2004 Aug;167(4):2121-5. [PubMed]
173. de Bono B, Madera M, Chothia C. VH gene segments in the mouse and human genomes. J Mol Biol. 2004 Sep 3;342(1):131-43. [PubMed] [PDF]
172. Gough J, Chothia C. The linked conservation of structure and function in a family of high diversity: the monomeric cupredoxins. Structure. 2004 Jun;12(6):917-25. [PubMed] [PDF]
171. Babu MM, Luscombe NM, Aravind L, Gerstein M, Teichmann SA. Structure and evolution of transcriptional regulatory networks. Curr Opin Struct Biol. 2004 Jun;14(3):283-91. Review. [PubMed]
170. Teichmann SA, Babu MM. Gene regulatory network growth by duplication. Nat Genet. 2004 May;36(5):492-6. [PubMed] [PDF]
169. Vogel C, Berzuini C, Bashton M, Gough J, Teichmann SA. Supra-domains: evolutionary units larger than single protein domains. J Mol Biol. 2004 Feb 20;336(3):809-23. [PubMed]
168. Vogel C, Bashton M, Kerrison ND, Chothia C, Teichmann SA. Structure, function and evolution of multidomain proteins. Curr Opin Struct Biol. 2004 Apr;14(2):208-16. Review. [PubMed] [PDF]
167. Schwabe JW, Teichmann SA. Nuclear receptors: the evolution of diversity. Sci STKE. 2004 Jan 20;2004(217):pe4. Review. [PubMed] [PDF]
166. Madera M, Vogel C, Kummerfeld SK, Chothia C, Gough J. The SUPERFAMILY database in 2004: additions and improvements. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D235-9. [PubMed] [PDF]
165. Andreeva A, Howorth D, Brenner SE, Hubbard TJ, Chothia C, Murzin AG. SCOP database in 2004: refinements integrate structure and sequence family data. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D226-9. [PubMed] [PDF]
164. Apic G, Huber W, Teichmann SA. Multi-domain protein families and domain pairs: comparison with known structures and a random model of domain recombination. J Struct Funct Genomics. 2003;4(2-3):67-78. [PubMed] [PDF]
163. Vogel C, Teichmann SA, Chothia C. The immunoglobulin superfamily in Drosophila melanogaster and Caenorhabditis elegans and the evolution of complexity. Development. 2003 Dec;130(25):6317-28. [PubMed] [PDF]
162. de Bono B, Chothia C. Exegesis: a procedure to improve gene predictions and its use to find immunoglobulin superfamily proteins in the human and mouse genomes. Nucleic Acids Res. 2003 Nov 1;31(21):6096-103. [PubMed] [PDF]
161. Bankier AT, Spriggs HF, Fartmann B, Konfortov BA, Madera M, Vogel C, Teichmann SA, et al. Integrated mapping, chromosomal sequencing and sequence analysis of Cryptosporidium parvum. Genome Res. 2003 Aug;13(8):1787-99. [PubMed] [PDF]
160. Babu MM. NCI: A server to identify non-canonical interactions in protein structures. Nucleic Acids Res. 2003 Jul 1;31(13):3345-8. [PubMed] [PDF]
159. Chothia C, Gough J, Vogel C, Teichmann SA. Evolution of the protein repertoire. Science. 2003 Jun 13;300(5626):1701-3. [PubMed] [PDF]
158. Singh SK, Babu MM, Balaram P. Registering alpha-helices and beta-strands using backbone C-H...O interactions. Proteins. 2003 May 1;51(2):167-71. [PubMed]
157. Madan Babu M. Did the loss of sigma factors initiate pseudogene accumulation in M. leprae? Trends Microbiol. 2003 Feb;11(2):59-61. [PubMed]
156. Madan Babu M, Teichmann SA. Evolution of transcription factors and the gene regulatory network in Escherichia coli. Nucleic Acids Res. 2003 Feb 15;31(4):1234-44. [PubMed] [PDF]
155. Madan Babu M, Teichmann SA. Functional determinants of transcription factors in Escherichia coli: protein families and binding sites. Trends Genet. 2003 Feb;19(2):75-9. [PubMed]
154. Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002 Dec 5;420(6915):563-73. [PubMed] [PDF]
153. Teichmann SA. The constraints protein-protein interactions place on sequence divergence. J Mol Biol. 2002 Nov 29;324(3):399-407. [PubMed]
152. Teichmann SA. Principles of protein-protein interactions. Bioinformatics. 2002;18 Suppl 2:S249. [PubMed] [PDF]
151. Madan Babu M, Kumar Singh S, Balaram P. A C-H triplebond O hydrogen bond stabilized polypeptide chain reversal motif at the C terminus of helices in proteins. J Mol Biol. 2002 Sep 27;322(4):871-80. [PubMed]
150. Teichmann SA, Babu MM. Conservation of gene co-regulation in prokaryotes and eukaryotes. Trends Biotechnol. 2002 Oct;20(10):407-10; discussion 410. [PubMed]
149. Hill EE, Morea V, Chothia C. Sequence conservation in families whose members have little or no sequence similarity: the four-helical cytokines and cytochromes. J Mol Biol. 2002 Sep 6;322(1):205-33. [PubMed] [PDF]
148. Rison SC, Teichmann SA, Thornton JM. Homology, pathway distance and chromosomal localization of the small molecule metabolism enzymes in Escherichia coli. J Mol Biol. 2002 May 3;318(3):911-32. [PubMed]
147. Jardine O, Gough J, Chothia C, Teichmann SA. Comparison of the small molecule metabolic enzymes of Escherichia coli and Saccharomyces cerevisiae. Genome Res. 2002 Jun;12(6):916-29. [PubMed] [PDF]
146. Madan Babu M, Sankaran K. DOLOP--database of bacterial lipoproteins. Bioinformatics. 2002 Apr;18(4):641-3. [PubMed] [PDF]
145. Babu MM, Kamalakkannan S, Subrahmanyam YV, Sankaran K. Shigella apyrase--a novel variant of bacterial acid phosphatases? FEBS Lett. 2002 Feb 13;512(1-3):8-12. [PubMed]
144. Bashton M, Chothia C. The geometry of domain combination in proteins. J Mol Biol. 2002 Jan 25;315(4):927-39. [PubMed] [PDF]
143. Gough J, Chothia C. SUPERFAMILY: HMMs representing all proteins of known structure. SCOP sequence searches, alignments and genome assignments. Nucleic Acids Res. 2002 Jan 1;30(1):268-72. [PubMed] [PDF]
142. Lo Conte L, Brenner SE, Hubbard TJ, Chothia C, Murzin AG. SCOP database in 2002: refinements accommodate structural genomics. Nucleic Acids Res. 2002 Jan 1;30(1):264-7. [PubMed] [PDF]
141. Teichmann SA, Rison SC, Thornton JM, Riley M, Gough J, Chothia C. Small-molecule metabolism: an enzyme mosaic. Trends Biotechnol. 2001 Dec;19(12):482-6. [PubMed]
140. Gough J, Karplus K, Hughey R, Chothia C. Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure. J Mol Biol. 2001 Nov 2;313(4):903-19. [PubMed] [PDF]
139. Teichmann SA, Rison SC, Thornton JM, Riley M, Gough J, Chothia C. The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli. J Mol Biol. 2001 Aug 24;311(4):693-708. [PubMed] [PDF]
138. Kister AE, Roytberg MA, Chothia C, Vasiliev JM, Gelfand IM. The sequence determinants of cadherin molecules. Protein Sci. 2001 Sep;10(9):1801-10. [PubMed]
137. Apic G, Gough J, Teichmann SA. An insight into domain combinations. Bioinformatics. 2001;17 Suppl 1:S83-9. [PubMed] [PDF]
136. Apic G, Gough J, Teichmann SA. Domain combinations in archaeal, eubacterial and eukaryotic proteomes. J Mol Biol. 2001 Jul 6;310(2):311-25. [PubMed]
135. Teichmann SA, Murzin AG, Chothia C. Determination of protein function, evolution and interactions by structural genomics. Curr Opin Struct Biol. 2001 Jun;11(3):354-63. Review. [PubMed] [PDF]
134. Qian J, Stenger B, Wilson CA, Lin J, Jansen R, Teichmann SA, Park J, et al. PartsList: a web-based system for dynamically ranking protein folds based on disparate attributes, including whole-genome expression and interaction information. Nucleic Acids Res. 2001 Apr 15;29(8):1750-64. [PubMed] [PDF]
133. Park J, Lappe M, Teichmann SA. Mapping protein family interactions: intramolecular and intermolecular protein family interaction repertoires in the PDB and yeast. J Mol Biol. 2001 Mar 30;307(3):929-38. [PubMed]
132. Hill E, Broadbent ID, Chothia C, Pettitt J. Cadherin superfamily proteins in Caenorhabditis elegans and Drosophila melanogaster. J Mol Biol. 2001 Feb 2;305(5):1011-24. [PubMed] [PDF]
131. Stoyanov O, Kister A, Gelfand I, Kulikowski C, Chothia C. Geometric invariant core for the CL and CH1 domains of immunoglobulin molecules. J Comput Biol. 2000;7(5):673-84. [PubMed] [PDF]
130. Park J, Holm L, Heger A, Chothia C. RSDB: representative protein sequence databases have high information content. Bioinformatics. 2000 May;16(5):458-64. [PubMed] [PDF]
129. Teichmann SA, Chothia C, Church GM, Park J. Fast assignment of protein structures to sequences using the intermediate sequence library PDB-ISL. Bioinformatics. 2000 Feb;16(2):117-24. [PubMed] [PDF]
128. Park J, Holm L, Chothia C. Sequence search algorithm assessment and testing toolkit (SAT). Bioinformatics. 2000 Feb;16(2):104-10. [PubMed] [PDF]
127. Teichmann SA, Chothia C. Immunoglobulin superfamily proteins in Caenorhabditis elegans. J Mol Biol. 2000 Mar 10;296(5):1367-83. [PubMed] [PDF]
126. Al-Lazikani B, Lesk AM, Chothia C. Canonical structures for the hypervariable regions of T cell alphabeta receptors. J Mol Biol. 2000 Jan 28;295(4):979-95. [PubMed] [PDF]
125. Teichmann SA, Mitchison G. Computing protein function. Nat Biotechnol. 2000 Jan;18(1):27. [PubMed]
124. Hamill SJ, Cota E, Chothia C, Clarke J. Conservation of folding and stability within a protein family: the tyrosine corner as an evolutionary cul-de-sac. J Mol Biol. 2000 Jan 21;295(3):641-9. [PubMed] [PDF]
123. Lo Conte L, Ailey B, Hubbard TJ, Brenner SE, Murzin AG, Chothia C. SCOP: a structural classification of proteins database. Nucleic Acids Res. 2000 Jan 1;28(1):257-9. [PubMed] [PDF]
122. Gerstein M, Chothia C. Perspectives: signal transduction. Proteins in motion. Science. 1999 Sep 10;285(5434):1682-3. [PubMed]
121. Tsai J, Taylor R, Chothia C, Gerstein M. The packing density in proteins: standard radii and volumes. J Mol Biol. 1999 Jul 2;290(1):253-66. [PubMed] [PDF]
120. Teichmann SA, Mitchison G. Is there a phylogenetic signal in prokaryote proteins? J Mol Evol. 1999 Jul;49(1):98-107. [PubMed] [PDF]
119. Teichmann SA, Chothia C, Gerstein M. Advances in structural genomics. Curr Opin Struct Biol. 1999 Jun;9(3):390-9. Review. [PubMed] [PDF]
118. Hubbard TJ, Ailey B, Brenner SE, Murzin AG, Chothia C. SCOP, Structural Classification of Proteins database: applications to evaluation of the effectiveness of sequence alignment methods and statistics of protein structural data. Acta Crystallogr D Biol Crystallogr. 1998 Nov 1;54(Pt 6 Pt 1):1147-54. [PubMed]
117. O'Reilly M, Teichmann SA, Rhodes D. Telomerases. Curr Opin Struct Biol. 1999 Feb;9(1):56-65. Review. [PubMed]
116. Lo Conte L, Chothia C, Janin J. The atomic structure of protein-protein recognition sites. J Mol Biol. 1999 Feb 5;285(5):2177-98. [PubMed] [PDF]
115. Teichmann SA, Mitchison G. Making family trees from gene families. Nat Genet. 1999 Jan;21(1):66-7. [PubMed]
114. Bycroft M, Bateman A, Clarke J, Hamill SJ, Sandford R, Thomas RL, Chothia C. The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease. EMBO J. 1999 Jan 15;18(2):297-305. [PubMed] [PDF]
113. Hubbard TJ, Ailey B, Brenner SE, Murzin AG, Chothia C. SCOP: a Structural Classification of Proteins database. Nucleic Acids Res. 1999 Jan 1;27(1):254-6. [PubMed] [PDF]
112. Teichmann SA, Park J, Chothia C. Structural assignments to the Mycoplasma genitalium proteins show extensive gene duplications and domain rearrangements. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14658-63. [PubMed] [PDF]
111. Park J, Karplus K, Barrett C, Hughey R, Haussler D, Hubbard T, Chothia C. Sequence comparisons using multiple sequences detect three times as many remote homologues as pairwise methods. J Mol Biol. 1998 Dec 11;284(4):1201-10. [PubMed] [PDF]
110. Bateman A, Murzin AG, Teichmann SA. Structure and distribution of pentapeptide repeats in bacteria. Protein Sci. 1998 Jun;7(6):1477-80. [PubMed]
109. Chothia C, Gelfand I, Kister A. Structural determinants in the sequences of immunoglobulin variable domain. J Mol Biol. 1998 May 1;278(2):457-79. [PubMed] [PDF]
108. Park J, Teichmann SA. DIVCLUS: an automatic method in the GEANFAMMER package that finds homologous domains in single- and multi-domain proteins. Bioinformatics. 1998;14(2):144-50. [PubMed] [PDF]
107. Brenner SE, Chothia C, Hubbard TJ. Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6073-8. [PubMed] [PDF]
106. Morea V, Tramontano A, Rustici M, Chothia C, Lesk AM. Antibody structure, prediction and redesign. Biophys Chem. 1997 Oct;68(1-3):9-16. [PubMed]
105. Morea V, Tramontano A, Rustici M, Chothia C, Lesk AM. Conformations of the third hypervariable region in the VH domain of immunoglobulins. J Mol Biol. 1998 Jan 16;275(2):269-94. [PubMed] [PDF]
104. Al-Lazikani B, Lesk AM, Chothia C. Standard conformations for the canonical structures of immunoglobulins. J Mol Biol. 1997 Nov 7;273(4):927-48. [PubMed] [PDF]
103. Park J, Teichmann SA, Hubbard T, Chothia C. Intermediate sequences increase the detection of homology between sequences. J Mol Biol. 1997 Oct 17;273(1):349-54. [PubMed] [PDF]
102. Sandford R, Sgotto B, Aparicio S, Brenner S, Vaudin M, Wilson RK, Chissoe S, et al. Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains. Hum Mol Genet. 1997 Sep;6(9):1483-9. [PubMed] [PDF]
101. Brenner SE, Chothia C, Hubbard TJ. Population statistics of protein structures: lessons from structural classifications. Curr Opin Struct Biol. 1997 Jun;7(3):369-76. Review. [PubMed] [PDF]
100. Chothia C, Gerstein M. Protein evolution. How far can sequences diverge? Nature. 1997 Feb 13;385(6617):579, 581. [PubMed] [PDF]
99. Chothia C, Jones EY. The molecular structure of cell adhesion molecules. Annu Rev Biochem. 1997;66:823-62. Review. [PubMed] [PDF]
98. Chothia C, Hubbard T, Brenner S, Barns H, Murzin A. Protein folds in the all-beta and all-alpha classes. Annu Rev Biophys Biomol Struct. 1997;26:597-627. Review. [PubMed] [PDF]
97. Hubbard TJ, Murzin AG, Brenner SE, Chothia C. SCOP: a structural classification of proteins database. Nucleic Acids Res. 1997 Jan 1;25(1):236-9. [PubMed] [PDF]
96. Fong S, Hamill SJ, Proctor M, Freund SM, Benian GM, Chothia C, Bycroft M, et al. Structure and stability of an immunoglobulin superfamily domain from twitchin, a muscle protein of the nematode Caenorhabditis elegans. J Mol Biol. 1996 Dec 6;264(3):624-39. [PubMed] [PDF]
95. Bateman A, Chothia C. Fibronectin type III domains in yeast detected by a hidden Markov model. Curr Biol. 1996 Dec 1;6(12):1544-7. [PubMed]
94. Bateman A, Jouet M, MacFarlane J, Du JS, Kenwrick S, Chothia C. Outline structure of the human L1 cell adhesion molecule and the sites where mutations cause neurological disorders. EMBO J. 1996 Nov 15;15(22):6050-9. [PubMed] [PDF]
93. Gerstein M, Chothia C. Packing at the protein-water interface. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10167-72. [PubMed] [PDF]
92. Bateman A, Eddy SR, Chothia C. Members of the immunoglobulin superfamily in bacteria. Protein Sci. 1996 Sep;5(9):1939-41. [PubMed] [PDF]
91. Brenner SE, Chothia C, Hubbard TJ, Murzin AG. Understanding protein structure: using scop for fold interpretation. Methods Enzymol. 1996;266:635-43. [PubMed]
90. Bateman A, Chothia C. Outline structures for the extracellular domains of the fibroblast growth factor receptors. Nat Struct Biol. 1995 Dec;2(12):1068-74. Review. [PubMed] [PDF]
89. Brenner SE, Hubbard T, Murzin A, Chothia C. Gene duplications in H. influenzae. Nature. 1995 Nov 9;378(6553):140. [PubMed] [PDF]
88. Tomlinson IM, Cox JP, Gherardi E, Lesk AM, Chothia C. The structural repertoire of the human V kappa domain. EMBO J. 1995 Sep 15;14(18):4628-38. [PubMed] [PDF]
87. Murzin AG, Brenner SE, Hubbard T, Chothia C. SCOP: a structural classification of proteins database for the investigation of sequences and structures. J Mol Biol. 1995 Apr 7;247(4):536-40. [PubMed] [PDF]
86. Barré S, Greenberg AS, Flajnik MF, Chothia C. Structural conservation of hypervariable regions in immunoglobulins evolution. Nat Struct Biol. 1994 Dec;1(12):915-20. [PubMed] [PDF]
85. Harpaz Y, Gerstein M, Chothia C. Volume changes on protein folding. Structure. 1994 Jul 15;2(7):641-9. [PubMed] [PDF]
84. Gerstein M, Lesk AM, Chothia C. Structural mechanisms for domain movements in proteins. Biochemistry. 1994 Jun 7;33(22):6739-49. Review. [PubMed] [PDF]
83. Harpaz Y, Chothia C. Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains. J Mol Biol. 1994 May 13;238(4):528-39. [PubMed] [PDF]
82. Murzin AG, Lesk AM, Chothia C. Principles determining the structure of beta-sheet barrels in proteins. II. The observed structures. J Mol Biol. 1994 Mar 11;236(5):1382-400. [PubMed] [PDF]
81. Murzin AG, Lesk AM, Chothia C. Principles determining the structure of beta-sheet barrels in proteins. I. A theoretical analysis. J Mol Biol. 1994 Mar 11;236(5):1369-81. [PubMed] [PDF]
80. Gerstein M, Sonnhammer EL, Chothia C. Volume changes in protein evolution. J Mol Biol. 1994 Mar 4;236(4):1067-78. [PubMed] [PDF]
79. Chothia C. Protein families in the metazoan genome. Dev Suppl. 1994:27-33. Review. [PubMed]
78. Chothia C, Murzin AG. New folds for all-beta proteins. Structure. 1993 Dec 15;1(4):217-22. Review. [PubMed]
77. Gerstein M, Anderson BF, Norris GE, Baker EN, Lesk AM, Chothia C. Domain closure in lactoferrin. Two hinges produce a see-saw motion between alternative close-packed interfaces. J Mol Biol. 1993 Nov 20;234(2):357-72. [PubMed] [PDF]
76. Gerstein M, Schulz G, Chothia C. Domain closure in adenylate kinase. Joints on either side of two helices close like neighboring fingers. J Mol Biol. 1993 Jan 20;229(2):494-501. [PubMed] [PDF]
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73. Chothia C. Proteins. One thousand families for the molecular biologist. Nature. 1992 Jun 18;357(6379):543-4. [PubMed] [PDF]
72. Murzin AG, Lesk AM, Chothia C. beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors. J Mol Biol. 1992 Jan 20;223(2):531-43. [PubMed] [PDF]
71. Stein P, Chothia C. Serpin tertiary structure transformation. J Mol Biol. 1991 Sep 20;221(2):615-21. Review. [PubMed] [PDF]
70. Gerstein M, Chothia C. Analysis of protein loop closure. Two types of hinges produce one motion in lactate dehydrogenase. J Mol Biol. 1991 Jul 5;220(1):133-49. [PubMed] [PDF]
69. Van Beeumen J, Van Bun S, Canters GW, Lommen A, Chothia C. The structural homology of amicyanin from Thiobacillus versutus to plant plastocyanins. J Biol Chem. 1991 Mar 15;266(8):4869-77. [PubMed] [PDF]
68. Chothia C. Asymmetry in protein structures. Ciba Found Symp. 1991;162:36-49; discussion 49-57. Review. [PubMed]
67. Janin J, Chothia C. The structure of protein-protein recognition sites. J Biol Chem. 1990 Sep 25;265(27):16027-30. Review. [PubMed] [PDF]
66. Tramontano A, Chothia C, Lesk AM. Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins. J Mol Biol. 1990 Sep 5;215(1):175-82. [PubMed] [PDF]
65. Chothia C, Finkelstein AV. The classification and origins of protein folding patterns. Annu Rev Biochem. 1990;59:1007-39. Review. [PubMed] [PDF]
64. Chothia C, Lesk AM, Tramontano A, Levitt M, Smith-Gill SJ, Air G, Sheriff S, et al. Conformations of immunoglobulin hypervariable regions. Nature. 1989 Dec 21-28;342(6252):877-83. Review. [PubMed] [PDF]
63. Creighton TE, Chothia C. Protein structure. Selecting buried residues. Nature. 1989 May 4;339(6219):14-5. [PubMed] [PDF]
62. Chothia C. Polyhedra for helical proteins. Nature. 1989 Jan 19;337(6204):204-5. [PubMed] [PDF]
61. Lesk AM, Brändén CI, Chothia C. Structural principles of alpha/beta barrel proteins: the packing of the interior of the sheet. Proteins. 1989;5(2):139-48. [PubMed]
60. Tramontano A, Chothia C, Lesk AM. Structural determinants of the conformations of medium-sized loops in proteins. Proteins. 1989;6(4):382-94. [PubMed] [PDF]
59. Chothia C, Boswell DR, Lesk AM. The outline structure of the T-cell alpha beta receptor. EMBO J. 1988 Dec 1;7(12):3745-55. [PubMed] [PDF]
58. Janin J, Miller S, Chothia C. Surface, subunit interfaces and interior of oligomeric proteins. J Mol Biol. 1988 Nov 5;204(1):155-64. [PubMed] [PDF]
57. Lesk AM, Chothia C. Elbow motion in the immunoglobulins involves a molecular ball-and-socket joint. Nature. 1988 Sep 8;335(6186):188-90. [PubMed] [PDF]
56. Chothia C. Protein structure: the 14th barrel rolls out. Nature. 1988 Jun 16;333(6174):598-9. [PubMed]
55. Chothia C, Lesk AM. Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol. 1987 Aug 20;196(4):901-17. [PubMed] [PDF]
54. Miller S, Janin J, Lesk AM, Chothia C. Interior and surface of monomeric proteins. J Mol Biol. 1987 Aug 5;196(3):641-56. [PubMed] [PDF]
53. Miller S, Lesk AM, Janin J, Chothia C. The accessible surface area and stability of oligomeric proteins. Nature. 1987 Aug 27-Sep 2;328(6133):834-6. [PubMed] [PDF]
52. Bashford D, Chothia C, Lesk AM. Determinants of a protein fold. Unique features of the globin amino acid sequences. J Mol Biol. 1987 Jul 5;196(1):199-216. [PubMed] [PDF]
51. Chothia C, Lesk AM. The evolution of protein structures. Cold Spring Harb Symp Quant Biol. 1987;52:399-405. [PubMed]
50. Chothia C, Lesk AM. The "crystalline molecule" image of proteins. Gazz Chim Ital. 1986;116:557-60. [PDF]
49. Lesk AM, Levitt M, Chothia C. Alignment of the amino acid sequences of distantly related proteins using variable gap penalties. Protein Eng. 1986 Oct-Nov;1(1):77-8. [PubMed] [PDF]
48. Chothia C, Lesk AM, Levitt M, Amit AG, Mariuzza RA, Phillips SE, Poljak RJ. The predicted structure of immunoglobulin D1.3 and its comparison with the crystal structure. Science. 1986 Aug 15;233(4765):755-8. [PubMed]
47. Chothia C, Lesk AM. The relation between the divergence of sequence and structure in proteins. EMBO J. 1986 Apr;5(4):823-6. [PubMed] [PDF]
46. Lesk AM, Chothia C. The response of protein structures to amino-acid sequence changes. Philos Trans R Soc Lond A. 1986 Apr 30;317(1540):345-56. [PDF]
45. Chothia C, Novotný J, Bruccoleri R, Karplus M. Domain association in immunoglobulin molecules. The packing of variable domains. J Mol Biol. 1985 Dec 5;186(3):651-63. [PubMed] [PDF]
44. Lesk AM, Janin J, Wodak S, Chothia C. Haemoglobin: the surface buried between the alpha 1 beta 1 and alpha 2 beta 2 dimers in the deoxy and oxy structures. J Mol Biol. 1985 May 25;183(2):267-70. [PubMed]
43. Chothia C, Lesk AM. Helix movements in proteins. Trends Biochem Sci. 1985 Mar;10(3):116-118. [PDF]
42. Chothia C, Lesk AM. Helix movements and the reconstruction of the haem pocket during the evolution of the cytochrome c family. J Mol Biol. 1985 Mar 5;182(1):151-8. [PubMed] [PDF]
41. Janin J, Chothia C. Domains in proteins: definitions, location, and structural principles. Methods Enzymol. 1985;115:420-30. [PubMed]
40. Dodson G, Chothia C. Fifty years of pepsin crystals. Nature. 1984 May 24-30;309(5966):309. [PubMed]
39. Lesk AM, Chothia C. Mechanisms of domain closure in proteins. J Mol Biol. 1984 Mar 25;174(1):175-91. [PubMed] [PDF]
38. Chothia C. Principles that determine the structure of proteins. Annu Rev Biochem. 1984;53:537-72. Review. [PubMed] [PDF]
37. Chothia C, Lesk AM, Dodson GG, Hodgkin DC. Transmission of conformational change in insulin. Nature. 1983 Apr 7;302(5908):500-5. [PubMed] [PDF]
36. Chothia C. Coiling of beta-pleated sheets. J Mol Biol. 1983 Jan 5;163(1):107-17. [PubMed] [PDF]
35. Lesk AM, Chothia C. Evolution of proteins formed by beta-sheets. II. The core of the immunoglobulin domains. J Mol Biol. 1982 Sep 15;160(2):325-42. [PubMed] [PDF]
34. Chothia C, Lesk AM. Evolution of proteins formed by beta-sheets. I. Plastocyanin and azurin. J Mol Biol. 1982 Sep 15;160(2):309-23. [PubMed] [PDF]
33. Chothia C, Janin J. Orthogonal packing of beta-pleated sheets in proteins. Biochemistry. 1982 Aug 17;21(17):3955-65. [PubMed] [PDF]
32. Mauguen Y, Hartley RW, Dodson EJ, Dodson GG, Bricogne G, Chothia C, Jack A. Molecular structure of a new family of ribonucleases. Nature. 1982 May 13;297(5862):162-4. [PubMed] [PDF]
31. Chothia C, Janin J. Relative orientation of close-packed beta-pleated sheets in proteins. Proc Natl Acad Sci U S A. 1981 Jul;78(7):4146-50. [PubMed] [PDF]
30. Chothia C, Levitt M, Richardson D. Helix to helix packing in proteins. J Mol Biol. 1981 Jan 5;145(1):215-50. [PubMed] [PDF]
29. Janin J, Chothia C. Packing of alpha-helices onto beta-pleated sheets and the anatomy of alpha/beta proteins. J Mol Biol. 1980 Oct 15;143(1):95-128. [PubMed] [PDF]
28. Lesk AM, Chothia C. Solvent accessibility, protein surfaces, and protein folding. Biophys J. 1980 Oct;32(1):35-47. [PubMed]
27. Lesk AM, Chothia C. How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins. J Mol Biol. 1980 Jan 25;136(3):225-70. [PubMed] [PDF]
26. Baldwin J, Chothia C. Haemoglobin: the structural changes related to ligand binding and its allosteric mechanism. J Mol Biol. 1979 Apr 5;129(2):175-220. [PubMed] [PDF]
25. Janin J, Chothia C. Role of hydrophobicity in the binding of coenzymes. Appendix. Translational and rotational contribution to the free energy of dissociation. Biochemistry. 1978 Jul 25;17(15):2943-8. [PubMed] [PDF]
24. Chothia C, Levitt M, Richardson D. Structure of proteins: packing of alpha-helices and pleated sheets. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4130-4. [PubMed] [PDF]
23. Chothia C, Wodak S, Janin J. Role of subunit interfaces in the allosteric mechanism of hemoglobin. Proc Natl Acad Sci U S A. 1976 Nov;73(11):3793-7. [PubMed] [PDF]
22. Chothia C, Baker RW, Pauling P. Conformation of acetylcholine at muscarinic nerve receptors: crystal and molecular structure of 2-trimethylammoniummethyl-5-methyl furan iodide (5-methylfurmethide iodide). J Mol Biol. 1976 Aug 25;105(4):517-26. [PubMed]
21. Chothia C. The nature of the accessible and buried surfaces in proteins. J Mol Biol. 1976 Jul 25;105(1):1-12. [PubMed] [PDF]
20. Levitt M, Chothia C. Structural patterns in globular proteins. Nature. 1976 Jun 17;261(5561):552-8. [PubMed] [PDF]
19. Janin J, Chothia C. Stability and specificity of protein-protein interactions: the case of the trypsin-trypsin inhibitor complexes. J Mol Biol. 1976 Jan 15;100(2):197-211. [PubMed] [PDF]
18. Chothia C, Leuzinger W. Acetylcholinesterase: the structure of crystals of a globular form from electric eel. J Mol Biol. 1975 Sep 5;97(1):55-60. [PubMed] [PDF]
17. Chothia C, Janin J. Principles of protein-protein recognition. Nature. 1975 Aug 28;256(5520):705-8. [PubMed] [PDF]
16. Chothia C. Structural invariants in protein folding. Nature. 1975 Mar 27;254(5498):304-8. [PubMed] [PDF]
15. Sweet RM, Wright HT, Janin J, Chothia CH, Blow DM. Crystal structure of the complex of porcine trypsin with soybean trypsin inhibitor (Kunitz) at 2.6-A resolution. Biochemistry. 1974 Sep 24;13(20):4212-28. [PubMed] [PDF]
14. Chothia C. Hydrophobic bonding and accessible surface area in proteins. Nature. 1974 Mar 22;248(446):338-9. [PubMed] [PDF]
13. Chothia C. Conformation of twisted beta-pleated sheets in proteins. J Mol Biol. 1973 Apr 5;75(2):295-302. [PubMed] [PDF]
12. Baker RW, Chothia C, Pauling P, Weber HP. Molecular structures of hallucinogenic substances: lysergic acid diethylamide, psilocybin, and 2,4,5-trimethoxyamphetamine. Mol Pharmacol. 1973 Jan;9(1):23-32. [PubMed] [PDF]
11. Baker RW, Chothia C, Pauling P, Weber HP. Molecular structure of LSD. Science. 1972 Nov 10;178(61):614-5. [PubMed]
10. Chothia C, Pauling P. Molecular models. Nature. 1971 Jan 22;229(5282):281. [PubMed]
9. Baker RW, Chothia CH, Pauling P, Petcher TJ. Structure and activity of muscarinic stimulants. Nature. 1971 Apr 16;230(5294):439-45. [PubMed] [PDF]
8. Chothia C. Structure activity relationships of some muscarinic agonists: a reply to Shefter and Triggle. Nature. 1970 Sep 26;227(5265):1355-6. [PubMed] [PDF]
7. Chothia C, Pauling P. Absolute configuration of cholinergic molecules; the crystal structure of (plus)-trans-2-aceoxy cyclopropyl trimethylammonium iodide. Nature. 1970 May 9;226(5245):541-2. [PubMed]
6. Chothia C, Pauling P, Petcher TJ. The conformations of cholinergic agonists. Br J Pharmacol. 1970 May;39(1):219P. [PubMed]
5. Chothia C, Pauling P. The conformation of cholinergic molecules at nicotinic nerve receptors. Proc Natl Acad Sci U S A. 1970 Mar;65(3):477-82. [PubMed] [PDF]
4. Chothia C. Interaction of acetylcholine with different cholinergic nerve receptors. Nature. 1970 Jan 3;225(5227):36-8. [PubMed] [PDF]
3. Chothia C, Pauling P. Conformation of cholinergic molecules relevant to acetylcholinesterase. Nature. 1969 Aug 30;223(5209):919-21. [PubMed] [PDF]
2. Chothia C, Pauling P. On the conformations of hallucinogenic molecules and their correlation. Proc Natl Acad Sci U S A. 1969 Aug;63(4):1063-70. [PubMed] [PDF]
1. Chothia C, Pauling P. Conformations of acetylcholine. Nature. 1968 Sep 14;219(5159):1156-7. [PubMed] [PDF]