Evolution of Transcription Factors and the Gene Regulatory Network in Escherichia coli

Supplementary Material
Reprint of the manuscript as a PDF

M. Madan Babu and Sarah A. Teichmann

MRC Laboratory of Molecular Biology, Hills Road, Cambridge - CB2 2QH, United Kingdom
Phone: +44-(0)1223-402041 :: Fax: +44-(0)1223-213556

Trancription factors play a central role in an organism by responding to the various stimuli in the external environment and regulating the expression of specific set of genes. In a simple organism like E. coli, we have identified 271 transcription factors and have studied the protein families and the domain architecture of the transcription factors. The supplementary material contains information about the individual transcription factors which have been identified, with searchable information about the domain architecture, protein function, etc

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The search query can contain the gene name, domain name, description of the gene, etc.

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Search the function field in the GenBank file


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Complete domain assignments for the 271 TFs with key

Clicking Here will take you to a page which contains representative domain architecture (not to scale) of the 271 identified TFs with the key to the figures used to represent domains.

Raw Data

Clicking here will provide you the information in a tab delimited format about the domain architecture, function, etc.

Clicking here will provide you the information in a tab delimited format about the transcription factors and the regulated genes

Relevant references

This page was last updated on: 27th August 2002






Since 27th Aug 2002