Emergence of modularity in protein interaction networks

This is the supplementary web site for the paper:

Pereira-Leal, JB, Levy, ED, Kamp, C & Teichmann, SA (2005) Evolution of functional modules in protein interaction networks

Clusters in PINs

  • Yeast - C=1 with paralogous interactions
  • Yeast-large - C=1 with paralogous interactions
  • Graph representations of PQS complexes

    all non-redundant complexes grouped according to types of contacts

  • identical
  • paralogous
  • identical & paralogous
  • different
  • identical & different
  • paralogous and different
  • identical & paralogous & different
  • Evolutionary roles of homomeric to paralogous oligomers

  • homomeric to paralogous oligomer with conserved topology

  • Jose Pereira-Leal
    Last modified: Thu May 19 18:33:32 BST 2005