Chitobiase


PDB code: 1c7s
E.C. Number: 3.2.1.52
Oligomeric unit: monomer
No of residues: 885
Topology diagram:


PDB
SCOP
CATH
IBM-JENA
MMDB
FSSP
Relibase


Ramachandran Phi Psi values:

Global summary of BLAST search:

QUERY= Submission, 885 bases, 4F53D169 checksum. 

                        |==================================================|885
>CHB_SERMA        4684  1 -------------------------------------------------- (CHB)CHITOBIASE PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA-GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Serratia marcescens]
>Q9ZN69           4577  1 -------------------------------------------------- (NAG1)N-ACETYL-BETA-D-GLUCOSAMINIDASE.[Enterobacter sp]
>Q9KPZ5          -1089526563  1  -----------------------------------------------   (VC2217)BETA-N-ACETYLHEXOSAMINIDASE.[Vibrio cholerae]
>CHB_VIBHA       -1092991061  1  ------------------------------------------------- (CHB)N,N'-DIACETYLCHITOBIASE PRECURSOR (EC 3.2.1.52) (CHITOBIASE) (N- ACETYL-BETA-GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Vibrio harveyi]
>Q9F9B4          795116559  1 -----------------------------------------------    CHITOBIASE.[Aeromonas hydrophila]
>Q9F1K5          1135039344  1   -------------------------------------------      (BCC1)CHITINASE.[Burkholderia cepacia]
>HEX_VIBVU       -1402523104  1  ------------------------------------------------- (HEX)BETA-HEXOSAMINIDASE (EC 3.2.1.52) (N-ACETYL-BETA-GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (CHITOBIASE).[Vibrio vulnificus]
>Q9FAC5          594552623  1     --------------------------------------------   (NAGA)GLCNACASE A PRECURSOR.[Alteromonas sp.]
>Q9ZH38          980998944  1     --------------------------------------------   (CHIP)BETA-HEXOSAMINIDASE.[Pseudoalteromonas sp. S9]
>Q9LC82          963298823  1    ---------------------------------------------   BETA-N-ACETYLGLUCOSAMINIDASE.[Aeromonas sp. 10S-24]
>HEXB_ALTSO      1612820278  1     ----------------------------------------       (NAG096)BETA-HEXOSAMINIDASE B PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-GLCNACASE) (BETA-N-ACETYLHEXOSAMINIDASE) (BETA-NAHASE).[Alteromonas sp.]
>Q9R6Y9          1768236047  1   ----------------------------------------------   (HEX99)TRANSGLYCOSYLATIVE ENZYME PRECURSOR.[Alteromonas sp.]
>Q9KUB0          1862313600  1                ------------------------------      (VC0613)BETA-N-ACETYLHEXOSAMINIDASE.[Vibrio cholerae]
>HEX1_VIBFU      1862313547  1                ---------------------------         (EXO..)BETA-HEXOSAMINIDASE (EC 3.2.1.52) (N-ACETYL-BETA-GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Vibrio furnissii]
>Q60081          -1024567209  1                ------------------------------      (CHB)BETA-N-HEXOSAMINIDASE (EC 3.2.1.14) (CHITINASE) (CHITODEXTRINASE) (1,4-BETA-POLY-N-ACETYLGLUCOSAMINIDASE) (POLY-BETA-GLUCOSAMINIDASE).[Vibrio parahaemolyticus]
>HEXA_PORGI      1266864988  1             ---------------------------------      (NAHA)BETA-HEXOSAMINIDASE PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-GLCNACASE) (BETA-N-ACETYLHEXOSAMINIDASE) (BETA-NAHASE).[Porphyromonas gingivalis]
>Q9L1V1          -477269192  1                -----------------------------       (SCE59.02C)PUTATIVE SUGAR HYDROLASE.[Streptomyces coelicolor]
>Q9PF31          -201829364  1                 --------------------------         (XF0847)BETA-HEXOSAMINIDASE PRECURSOR.[Xylella fastidiosa]
>Q9ZH39          994042268  1               -----------------------------        (CHIQ)BETA-N-ACETYLGLUCOSAMINIDASE.[Pseudoalteromonas sp. S9]
>CAC34802        872315142  1                ---------------------------         (hex56)Beta-N-Acetylhexosaminidase precursor (EC 3.2.1.52).[Streptomyces olivaceoviridis]
>Q9L068          -127061701  1                 --------------------------         (HEXA)BETA-N-ACETYLHEXOSAMINIDASE.[Streptomyces coelicolor]
>O85361          -948256099  1                 --------------------------         (HEX)B-N-ACETYLHEXOSAMINIDASE.[Streptomyces plicatus]
>Q9RHV6          539169969  1                 --------------------------         (NAGB)BETA-N-ACETYLGLUCOSAMINIDASE PRECURSOR.[Streptomyces thermoviolaceus]
>Q9L448          743927357  1                ---------------                     (CHB)CHITOBIASE PRECURSOR (EC 3.2.1.52).[Arthrobacter sp]
>Q9L448          -1949344531  1                                     ----------     (CHB)CHITOBIASE PRECURSOR (EC 3.2.1.52).[Arthrobacter sp]
>Q9RK76          -2070156915  1             -------------------------------        (SCF11.14)PUTATIVE BETA-HEXOSAMINIDASE.[Streptomyces coelicolor]
>Q9HGI3          -2094500684  1              -----------------------------         (NAGA)N-ACETYLGLUCOSAMINIDASE.[Emericella nidulans]
>Q9GPG8          444470895  1             --------------------------------       BETA-N-ACETYLGLUCOSAMINIDASE.[Bombyx mandarina]
>Q9KI44          796993697  1                ---------------------------         (NAGA)BETA N-ACETYLGLUCOSAMINIDASE.[Cellulomonas sp. GM13]
>HEXC_BOMMO      -352899904  1                ---------------------------         CHITOOLIGOSACCHARIDOLYTIC BETA-N-ACETYLGLUCOSAMINIDASE PRECURSOR (EC 3.2.1.52) (BETA-GLCNACASE) (BETA-HEXOSAMINIDASE) (BETA-N- ACETYLHEXOSAMINIDASE).[Bombyx mori]
>Q9VZE3          1717433747  1               ----------------------------         (HEXO1..)HEXO1 PROTEIN.[Drosophila melanogaster]
>P78738          -1021111407  1                -----------                         (EXC1)EXOCHITINASE.[Trichoderma harzianum]
>Q9URR8          1104100643  1                  -------------------------         (HEX)BETA-N-ACETYLHEXOSAMINIDASE PRECURSOR (EC 3.2.1.52).[Penicillium chrysogenum]
>HEX1_CANAL      -1913407650  1               -----------                          (HEX1)BETA-HEXOSAMINIDASE PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-GLCNACASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Candida albicans]
>HEX1_CANAL      -1795078039  1                                    -------         (HEX1)BETA-HEXOSAMINIDASE PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-GLCNACASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Candida albicans]
>HEXA_DICDI      -1285822159  1             ------------------------------         (NAGA)BETA-HEXOSAMINIDASE A PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Dictyostelium discoideum]
>O18795          2136528418  1                  -------------                     (HEXB)BETA-N-ACETYLHEXOSAMINIDASE BETA SUBUNIT (EC 3.2.1.52).[Felis silvestris catus]
>HEXA_CAEEL      -1151168261  1                ---------------------------         (T14F9.3)PROBABLE BETA-HEXOSAMINIDASE A PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE).[Caenorhabditis elegans]
>HEXB_FELCA      2136528418  1                  -------------                     (HEXB)BETA-HEXOSAMINIDASE BETA CHAIN PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (HEXOSAMINIDASE A) (FRAGMENT).[Felis silvestris catus]
>Q9W3C4          1799927118  1                ---------------                     (HEXO2..)PUTATIVE BETA-N-ACETYLHEXOSAMINIDASE HEXO2 (EC 3.2.1.52).[Drosophila melanogaster]
>HEXB_MOUSE      702386926  1                  ------------------------          (HEXB)BETA-HEXOSAMINIDASE BETA CHAIN PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (HEXOSAMINIDASE A).[Mus musculus]
>P78739          1418924910  1                ----------                          (EXC2)EXOCHITINASE.[Trichoderma harzianum]
>P87258          -530713231  1               ----------------------------         (NAG1)N-ACETYL-BETA-D-GLUCOSAMINIDASE.[Trichoderma harzianum]
>Q9SYK0          1370992581  1                ---------------------------         (F3F20.4)F3F20.4 PROTEIN.[Arabidopsis thaliana]
>HEXA_HUMAN      -1681068331  1                 -------------------------          (HEXA)BETA-HEXOSAMINIDASE ALPHA CHAIN PRECURSOR (EC 3.2.1.52) (N-ACETYL- BETA-GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (HEXOSAMINIDASE A).[Homo sapiens]
>HEXA_MOUSE      -1715428076  1                 -------------------------          (HEXA)BETA-HEXOSAMINIDASE ALPHA CHAIN PRECURSOR (EC 3.2.1.52) (N-ACETYL- BETA-GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (HEXOSAMINIDASE A).[Mus musculus]
>AAH01138        -1681068336  1                  ------------------------          Similar to hexosaminidase A (alpha polypeptide) (Fragment).[Homo sapiens]
>HEXB_PIG        -687194502  1                ---------------                     (HEXB)BETA-HEXOSAMINIDASE BETA CHAIN PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (HEXOSAMINIDASE A) (65 KDA EPIDIDYMAL BOAR PROTEIN).[Sus scrof>HEXB_HUMAN      148973670  1                  ------------------------          (HEXB)BETA-HEXOSAMINIDASE BETA CHAIN PRECURSOR (EC 3.2.1.52) (N-ACETYL-BETA- GLUCOSAMINIDASE) (BETA-N-ACETYLHEXOSAMINIDASE) (HEXOSAMINIDASE A).[Homo sapiens]
>Q9V6C8          -25794751  1                 ---------                          (CG8824)CG8824 PROTEIN.[Drosophila melanogaster]
>P90609            175  1                   ----                             BETA-HEXOSAMINIDASE (FRAGMENT).[Tritrichomonas foetus]
>Q9M3C5          -903830348  1                ----------                          (T26I12.140)BETA-N-ACETYLHEXOSAMINIDASE-LIKE PROTEIN.[Arabidopsis thaliana]

Global alignment of BLAST search:

                     10        20        30        40        50        60        70        80        90        100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580       590       600       610       620       630       640       650       660       670       680       690       700       710       720       730       740       750       760       770       780       790       800       810       820       830       840       850       860       870       880
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Your query : MNAFKLSALARLTATMGFLGGMGSAMADQQLVDQLSQLKLNVKMLDNRAGENGVDCAALGADWASCNRVLFTLSNDGQAIDGKDWVIYFHSPRQTLRVDNDQFKIAHLTGDLYKLEPTAKFSGFPAGKAVEIPVVAEYWQLFRNDFLPRWYATSGDAKPKMLANTDTENLDQFVAPFTGDQWKRTKDDKNILMTPASRFVSNADLQTLPAGALRGKIVPTPMQVKVHAQDADLRKGVALDLSTLVKPAADVVSQRFALLGVPVQTNGYPIKTDIQPGKFKGAMAVSGAYELKIGKKEAQVIGFDQAGVFYGLQSILSLVPSDGSGKIATLDASDAPRFPYRGIFLDVARNFHKKDAVLRLLDQMAAYKLNKFHFHLSDDEGWRIEIPGLPELTEVGGQRCHDLSETTCLLPQYGQGPDVYGGFFSRQDYIDIIKYAQARQIEVIPEIDMPAHARAAVVSMEARYKKLHAAGKEQEANEFRLVDPTDTSNTTSVQFFNRQSYLNPCLDSSQRFVDKVIGEIAQMHKEAGQPIKTWHFGGDEAKNIRLGAGYTDKAKPEPGKGIIDQSNEDKPWAKSQVCQTMIKEGKVADMEHLPSYFGQEVSKLVKAHGIDRMQAWQDGLKDAESSKAFATSRVGVNFWDTLYWGGFDSVNDWANKGYEVVVSNPDYVYMDFPYEVNPDERGYYWGTRFSDERKVFSFAPDNMPQNAETSVDRDGNHFNAKSDKPWPGAYGLSAQLWSETQRTDPQMEYMIFPRALSVAERSWHRAGWEQDYRAGREYKGGETHFVDTQALEKDWLRFANILGQRELAKLDKGGVAYRLPVPGARVAAGKLEANIALPGLGIEYSTDGGKQWQRYDAKAKPAVSGEVQVRSVSPDGKRYSRAEKV 
CHB_SERMA  : MNAFKLSALARLTATMGFLGGMGSAMADQQLVDQLSQLKLNVKMLDNRAGENGVDCAALGADWASCNRVLFTLSNDGQAIDGKDWVIYFHSPRQTLRVDNDQFKIAHLTGDLYKLEPTAKFSGFPAGKAVEIPVVAEYWQLFRNDFLPRWYATSGDAKPKMLANTDTENLDQFVAPFTGDQWKRTKDDKNILMTPASRFVSNADLQTLPAGALRGKIVPTPMQVKVHAQDADLRKGVALDLSTLVKPAADVVSQRFALLGVPVQTNGYPIKTDIQPGKFKGAMAVSGAYELKIGKKEAQVIGFDQAGVFYGLQSILSLVPSDGSGKIATLDASDAPRFPYRGIFLDVARNFHKKDAVLRLLDQMAAYKLNKFHFHLSDDEGWRIEIPGLPELTEVGGQRCHDLSETTCLLPQYGQGPDVYGGFFSRQDYIDIIKYAQARQIEVIPEIDMPAHARAAVVSMEARYKKLHAAGKEQEANEFRLVDPTDTSNTTSVQFFNRQSYLNPCLDSSQRFVDKVIGEIAQMHKEAGQPIKTWHFGGDEAKNIRLGAGYTDKAKPEPGKGIIDQSNEDKPWAKSQVCQTMIKEGKVADMEHLPSYFGQEVSKLVKAHGIDRMQAWQDGLKDAESSKAFATSRVGVNFWDTLYWGGFDSVNDWANKGYEVVVSNPDYVYMDFPYEVNPDERGYYWGTRFSDERKVFSFAPDNMPQNAETSVDRDGNHFNAKSDKPWPGAYGLSAQLWSETQRTDPQMEYMIFPRALSVAERSWHRAGWEQDYRAGREYKGGETHFVDTQALEKDWLRFANILGQRELAKLDKGGVAYRLPVPGARVAAGKLEANIALPGLGIEYSTDGGKQWQRYDAKAKPAVSGEVQVRSVSPDGKRYSRAEKV  CHB_SERMA  
Q9ZN69     : MNAFKLSALAALTATMGFLGGMGSAMADQQLVDQLSQLKLNVKMLDNRAGENGVDCAALGADWASCNRVLFTLSNDGQAIDGKDWIIYFHSPRQTLRVDNDQFKIAHLTGDLYKLEPTAKFSGFPAGKAVEIPVVAEYWQLFRNDFLPRWYATSGDAKPKMLANTDTENLDQFVAPFTGDQWKRTKDDKNILMTPASRFVSNADLQTLPAGALRGQIVPTPMQVKVHEQDADLRNGVSPDLSTLDKPAADVVNQRFALLGVPVQANGYPIKTDIQPGKFKGAMAVPGAYELKIGKKEARVIGFDQAGVFYGLQSILSLVPTDGSGKIATLDASDAPRFQYRGIFLDVARNFHKKDAALRLLDQMAAYKLNKFHFHLSDDESWRIEIPGLPELTEVGGQRCHDLSETSCLLPQYGQGPDVYGGFFTRQDYIDIIKYAQARQIEVIPEIDMPAHARAAVVSMEARYKKLHAAGKEQEANEFRLVDPTDTSNTTSVQFFNRQSYLNPCLDSSQRFVDKVIGEIAQMHKEAGQPIKTWHFGGDEAKNIRLGAGYTDKAKPEPGKGIIDQSNEDKPWAKSQVCQVMIKEGKVADMEHLPSYFGQEVSKLVKAHGIDRMQAWQDGLKDAESSKAFATSRVGVNFWDTLYWGGFDSVNDWANKGYEVVVSNPDYVYMDFPYEVNPDERGYYWGTRFSDKRKVFSFAPDNMPQNAETSVDRDGNHFNAKSDKPWPGAYGLSAQLWSETQRTDPQMEYMIFPRALSVAERAWHRAGWEQDYRAGREYKGGETHFVDTKTLEKDWLRFANILGQRELAKLDKGGVAYRLPVPGARVAGGKLEANIALPGLGIEYSTDGGKQWQRYDAKAKPAVSGEVQVRSVSPDGKRYSRAEKV  Q9ZN69  
Q9KPZ5     :                             QEVVDTLANNLDVQYQVVNNHGADTGLACQTLEAEWASCNQVNMTLVNRGEAVNSKDWAIYFHSIRLILDVGNDQFKITRVTGDLHKLEPTDKFDGFAAGETVTLPLIGEYWTLFETDFMPRAFVTAPDAEPKVIAALNTEDVASFVSGLEGENLKRTPSDNNVFAQALSRFEKNSDVALQD---VTHALIPTPLQVKSHSGSVSIAKGIALPSKAFDGEQMQALNERAQLLGVNLK-GVMPAQVIINPKSFKGDLAKSGAYRLAITDKAVKVTAFDQAGAFYAMQSLLGLVDMADATQLPKVEIVDAPRFDYRGVMVDVARNFHSKQAILATLDQMAAYKMNKLHLHLTDDEGWRIEIPGLPELTDIGAQRCFDPSETECVLPQLGSGPNADNFGSGYFTKQDYLEILQYAKARHIEVIPEIDMPAHARAAVVSMEARYQRLMQEGNEAAANEFRLLDPQDTSNVTTVQFYDRMSFINPCLDSSKRFVDKVISEIAAMHQAAGMPLTTWHFGGDEAKNIKLGAGFQDVNTQEPVSWKGNLDLSKQDKPFARSPQCQNLIATGAVSDFGHLPSYFAEQVSKLVAEKGIPNFQAWQDGLKYSEGEKAFATENTRVNFWDVLYWGGSASAYEWAEKGYDVIISNPDYVYMDMPYEADPKERGYYWATRATDTRKMFGFAPENLPQNAETSLDRDGNGFSGKGEVKGKPFYGLSAQLWSETVRTDEQYEYMVFPRVLAAAERAWHRAEWENAYKVGVEY-SQETQLVNHKALNADWNRFANVLGQRELAKLEKAGIDYRLPVPGAKIENGHLAMNVQFPGVTLQYSLD-GQTWLDYDAKQAPKVSGEVWIRSVSASGERTSR  Q9KPZ5  
CHB_VIBHA  :                           SEQQVVNSLADNLDIQYEVLTNHGANEGLACQDMGAEWASCNKVNMTLVNQGEAVDSKDWAIYFHSIRLILDVDNEQFKISRVTGDLHKLEPTDKFDGFAAGEEVVLPLVGEYWQLFETDFMPGAFVSAPNAEPKMIASLNTEDVASFVTGLEGNNLKRTPDDNNVFANAVSRFEKNEDLATQDVSTT---LLPTPMHVEAGKGKVDIADGIALPKDAFDATQFAAIQDRAEVVGVDVRGD-LPVSITVVPADFTGELAKSGAYEMSIKGDGIVIKAFDQAGAFYAVQSIFGLVDSQNADSLPQLSIKDAPRFDYRGVMVDVARNFHSKDAILATLDQMAAYKMNKLHLHLTDDEGWRLEIPGLPELTEVGANRCFDTQEKSCLLPQLGSGPTTDNFGSGYFSKADYVEILKYAKARNIEVIPEIDMPAHARAAVVSMEARYDRLMEEGKEAEANEYRLMDPQDTSNVTTVQFYNKQSFINPCMESSTRFVDKVISEVAAMHQEAGAPLTTWHFGGDEAKNIKLGAGFQDVNAEDKVSWKGTIDLSKQDKPFAQSPQCQTLITDGTVSDFAHLPSHFAEEVSKIVAEKGIPNFQAWQDGLKYSDGEKAFATENTRVNFWDVLYWGGTSSVYEWSKKGYDVIVSNPDYVYMDMPYEVDPKERGYYWATRATDTRKMFGFAPENMPQNAETSVDRDGNGFTGKGEIEAKPFYGLSAQLWSETVRNDEQYEYMVFPRVLAAAQRAWHRADWENDYKVGVEY-SQNSNLVDKASLNQDYNRFANVLGQRELAKLEKSGIDYRLPVPGAKVEDGKLAMNVQFPGVTLQYSLD-GENWLTYADNARPNVTGEVFIRSVSATGEKVSRITSV  CHB_VIBHA  
Q9F9B4     :     KHSLLAIAMSTVFVSQVQAADAAKQAVVDSLANNLVVKYEVVTNDGAGAGLDCQALGSEWASCGVAKLHLTNTGADVTSKDWSIYVSSIRRIQRVDNDQFTITHLTGDLYRLTPTEKFQGFAKDATVEVPLVVEYWVLFESDIMPNWYVASEGAEPKVLASMSNINDASTYEKPMPADGWKRTKDDKNILMNSETRFAANQTSTLLPAGKIDNQILPTPMKQVVKVGPQVDFSTIKLNALDLPS---DRAEALKAQLTKLGVTLSDTGYPVTI-----KLGSKLKQAEGYDMTIGQKGTVIQGRDIDGAFWGAQSLISLLGVDDK-LVSPMTVEDAPRFEYRGMQTDVARHFRSLDTMKKLVDQMSAMKLNVLHLGLTNDEGWGLEIPGLPELTQVGSQRCHDESETKCLMPQLGSGPTSDNQGSGFYSKSDYVDLVRYAKARGVTVIPEINMPAHARAAVVSMEARYKRLMAEGKEAEANQFRLTDPADTSNVTSVQFYDKMSFINPCQPGAATFVAKVMDEVAQMHQAAGQPLTAWHYGGDEAKNIYQDPAVTKKEELVAWKGNVDSSKQDKPFGKSPMCQKRIDEGKIKEVGELPVYFAKEVGQMVKDRGFSTLQAWEDGRKYASGAKDFATDNTRVNFWETLYWGGFNEARKWAHKGYQVVLSNPDYLYFDFPNELHPAERGYYWATRFNDTRKVFAFAPENLPQNAETSVDRDGNAFVAKGDQDPVKFKGISGQQWRETVRTDAQYEYMVYPRFFSVAERAWHKGGFELDYVKNREF-SGETKFVNKATLNKEWNQFANVLGQRVLPKLDQAGVEYRLSVPGAKVVNGVLEANVDLPGLPIQYSLD-GTNWSVLHAASNP  Q9F9B4  
Q9F1K5     :                                      LALRVAVDNNHAAAAGVPCADLGADGAACATGRLILQNRGHQAIADGGWKLYLHSIRRLLRIDRPGFALRRLTGDLYELTPQPGSVRLAPGERIELPFVAEYWLLRYSDVIPRPYVVVDGAPPAVLRYNDTDDELRYVESLPADAQNNSTGN-------APPVAARPDATRALPSVKREQPLPGTL---------DLR-GVELALPNL--PDAQVAALRDRATTLGLDGARVPVWGAVAPRRLPADIATPGGYRLAIGPRGVFIEGYDRAGLYYGVQTLFSLAPA-GGGAIPAMLIEDAPRFTHRGMHVDLARNFKHPATLRRLIDQMSAYKLNRLHLHLSDDEGWRIEIPGLPELTEIGGRRCHDPSETRCLLPQLGSGPDNRSGGGYLTRDDYVALVRYAAAHFVEIIPEIDMPAHARAAVVTMEARYRRLHAAGREQEANAYRLLDPQDTSNLTTVQFYDRRSDLNPCVPGALNFASKVIREIAAMHADAQAPLHIWHYGGDEAKNIFLGAGFQPLNGTDPNKGRIDLAAQDKPWARSPACTALLQRGEIKSIDELPTRFAQQVSAAVNANGIDTMAAWQDGIKHANGPQDFSTRHVMVSLWDTIFWGASDSARDLSGKGYLTVLALPDYLYFDFPYTLNPRERGYYWGSHATDEYKVFSLAPENLPQNAEVMGDRDGNTFEVTGTGPAPRIEGMQGQAWGEVMRNDTFLEYMAYPRLLALAERAWHRADWELPYAAGVRYKRGDTHHVDTAALQRDWAGFATLLTQRELPKLDRAGVGYRKP  Q9F1K5  
HEX_VIBVU  :                            DQKDVDYAAK---NLKLTTSLVANKPKDCPP-EAPWGACYRVEINLENTGSKSLNENVEIYFSSIHRTLGSKSEEFKVEHINGDLHKITTTEKFKGLKGGKTKSFQVDFMNWIVSNSDFMPNYYVASEHLEGRNILNTVPIDAVHITEEVSGFTTGIKHTPNQLKRTANDLLPAATATTRYEQYSKVKDLGADAVSAHILPTPLETSVHEGSLNIAQGINIVSDALPADQVEALNFRFETLGVNTGT-GVPVNVTIKADSSKK----SGSYTLDVTSSGIRIVGVDKAGAFYGVQSLAGLV-TVGKDTINQVSINDEPRLDYRGMHMDVSRNFHSKELVFRFLDQMAAYKMNKFHFHLADDEGWRLEINGLPELTQVGAHRCHDVEQNKCMMPQLGSGAELPNNGSGYYTREDYKEILAYASARNIQVIPSMDMPGHSLAAVKSMEARYRKFMAEGDVVKAEMYLLSDPNDTTQYYSIQHY-QDNTINPCMESSFVFMDKVIDEINKLHKEGGQPLTDYHIGADETAGA---------------------------WGDSPECRKMFVAPESGVKNAKDINGYFINRISHILDAKGLT-LGAWNDGL----SHKALDASSLAGNPPKAWVWGTMFWGGVDQYNSFANKGYDVVVTPPDAYYFDMPYENDPEERGYYWATRFNDTKKVFSFMPENVPANVEWMTDRMGAKISATTGEKTHDFLGVQGALWSETIRTDAQVEYMVLPRMIAVAERGWHKASWEEEHKEGITYTSNVDGHEGTTHLNDNIATRDADWAHFSNILGYKEMPKLDKAGITYRLPVLGAVIKNNILDVVTEFHGVAIQYSLD-GKTWHKYDDTKKPQVSTKALVRSVSTNG-RTGRAVEV  HEX_VIBVU  
Q9FAC5     :                                                                                    DWQIYLHSVRHISTETAEGLRFEHINGDLHRITPTDSFAGLKAGEKLKLAFDGSAWIAAYSDFMPRAFIVSGKNKPVIFTNTDTEDMTQFVAPFERENQLKRYNTPTDYTQIANAALRFERNQSNISVSKEDALR-RINPKPEHIDFSRGEITLNKNWQIRFAGRLKSEVAVFQEDLSEYGLDLKAEANHVPEGNIPTIRLKVAKSLGRDYDYNQAGSYTLDIDDDVIEITGIDNAGVFYGIQSLLALFPADSNNEITLSHVEIKDSPRFSWRGMHYDNARNYHGKDALFKLIEQMARYKLNKFHWHFSDDEGWRLEIPGLPELTEVGAFRCFDLQERECLLTQLGTGPFKTGSGNGYLSREDFVELLKFATARHIEIIPEIESPGHARAAIKSMEARYHKLMEAGKAQEAKAYLLNDIDDTSKYLTVQLYTDNS-INVCLDSSYAFMEKVVYELQEMYRDAGTMLTTVHFGGDEV-----------------GKG---------SWTESPACNDLFAVADNGVAGPNDLKPYFTQKVAKLLAKRGI-TPAAWEDGLMYNTTTTFKRDEFPNPQFLVNTWDNIWEWGVADRAHRFANNNYQVILSHGTHLYFDHPYEAHPEERGYYWATRYTDTKKAFSYMPDNIYANADFTRNREPIVNLEALVGRELPALKRPQNILGMQGQIWSETIRSEDQVLRLIFPRLLSLAERAWHKADWE-----GRR--------INQKELNKDFSTFAAALSLKEIAKLQNDGIKPNLPVPGAKVVLGKLEANSAFPYLAIEVSLDNGESWQPYTDQMSISDESKVLLRT  Q9FAC5  
Q9ZH38     :                                                                                    NWQLYFHSIRKVKTPEAKGIAIEHVNGDLHRLVPTKAFAGLAVGETLALEYEAAAYIVSYSDVMPRAFISLDNKDAEVFASTDTEDLKQFVLPIVEERQLKKFNTPKDLSVIADAQNRHALNIKNEKYTPSQEDALK-RIIPKPLDVDFSRGEVTLSSDWVVSYQGSLKQEVNVLLDDLSKLYGLKLEANADHISVGKKPHLSLKVDNSIQSGDAESYHLEIDKNKITVVGSDNAGVFYGLQSLLALFPADTNGSVELPRVEIKDSPRFSYRGMHYDNARNFHGKDAMFKLVEQMAKYKLNTLHWHFSDDEGWRLEIPSLPELAEIGGVRCFDLSEDSCLLTQLGTGPHKDGSGNGYLTKDDFVELLKFAAARHIKIIPEVESPGHARASIKAMEARYRKLMKAGDEVGAKAYLLSDPEDKSKYITVQNYTDNS-INACMDSSYNFMEKVTYELQQMYREAGVRLENLHFGGDE-----VGAG---------------------SWTNSPACQKMFEEAGNGVAGPADLKPYFTQRVAKMLAKRGI-APGAWEDGLMYDRVNTFNREEFPNPVFTANAWDNIWEWGVADRAYRLANNDYQVVLSHGTHLYFDHPYEAHPEERGYYWATRFISNEKAFGYMPDNVYANADFT--RTGEVIKNLEDLVGRPLPQLEKPENILGMQGQVWSETIRTEDQYSYVV-PTRVAVAERAWYKAPWE-----------GEK--PDAQKRAKDWMTFSAALGTKELAKLAKSGVKANLDVPGGEVNKGTLTTSVATAYLDVEYSVDQGKSWQTYQ---QPVNVGDTQV  Q9ZH38  
Q9LC82     :                                                       ECIQNGHDGDNFIAELTLTNRSAVPLSGSGWGLYFNTARK-IRPESVTGGVAVSHVNGDLSRFTPTADFGTLQPGESRVIRYTGIFWVIQDTDALLGFYIVYGDGTPAARAEAIG---DPHIVPFTRPEVLNRNGADKVEPVTPATRYTANEKLSVLPAAEV-GKITPTPLSAQFGSGS------YAIDESTAILSGAELASEAALLRAIIHDVSGVWLQRAASGSGITLKIGAVNTTDTLAPNEAYELDISAAGIVITGASAHGVFNGIQSLRQLLPVDAFTNPLPTLAVQHGKVIDAPRFAYRGVHLDVGRNFSSKESVLRLLDCMALYKLNQFHFHLTDDEGWRVEIPSLPELTEIGSGRGFTITETDNLVPCFGSGAEVEGSHGTGFYTRAEFVEILKFATARHIEVVPEFDVPGHARSAIKAMNVRYDRLVKAGQQAEAEKYLLVDFDDKSKYESVQLWT-DNVICIAREGAYNFIETVIHDVKDMYAEAGAPWTTMHTGGDEVPH---GA-----------------------WEGSPICQKFMKDNALESIQELQDHFLARYRDILKKYGL-TFGGWEEIALKKETVEGVTHHGPNPKFVDANFRPYIWNNVWGWGQEDFAYQLANAGYKVVLCNVTNLYFDLAYEKDPKEPGYYWG-GFINTRKAYEFVPLDIYTTATVNLFGHDLGDSLKDKARLTPEGTKNVIGIQGELWGENLRDAGRLEYLAMPRIVALAERAWAKDPGWTQIADKTARDAK-----------MDADWNQFANRLGQRELPRLDGFVGGYGYRVPVPGAKLEGGKLHANIESPGFVLRYTTDGSEPTARSAEYTGPVAVSGTVKIAAFTSTNRR  Q9LC82  
HEXB_ALTSO :                                                                                    DFAIFFSQLMPIYHVEGDNFAITHINGDIHKITPAAGFSGFSSAPTT-VRFYTKDSQVTRSEVYAKLCCERTRSLKLTPQVIKSTQTQRDNDTGLDCNLNLTPFV---TLNQLQTSSKDDTPWM--GSEYLYQHQVKPTLDAAIG--LIPKPKQLTVLSDKRLNLAAGINLQLSGISADAIAMAQQRLNTLGVKSTKEGLVVNVAVKPNKQS-----SPHYQLTVAENNISIQGNNSAAAFYALQSLAGLLDINDL-RIPMVDIIDTPRYDFRGLHVDVARNFRSKAFILQTIEQMAAYKLNKLHLHLADDEGWRLAIDGLDELTSVGAYRCFDLTETRCLLPQLGAGNDKNAQVNGFYSAEDYIEILRYAKAHHIEVLPSLDMPGHSRAAIIAMEARYKKLMAQGKPEDAQKYRLVETADKTRYSSIQHYN-DNTLNVCIANTYTFIDKVLSEVKVLHDRAGVPLNTYHIGADETAVL---------------------------WLESPACKKL--QASVKDFTNFNGYFIERVAKLLDKKGI-QVAGWSDGLGDVRA--ANMPANIQSNGLGDIKRKRAPVAHRFANQGWQVVLSSPDVTYFDFPYQSHPEERGNHWASRAIESKKMFEFMPDNLPAHAEIWKNTNNHAYIANDSDSSLNKGVQFAGLQGHLWSEMLRSDAQAEYMLYPRLLALAERAWHHAEWELPYQAGRIYSQSSGYFTAKLQAQREADWQRFVAILG  HEXB_ALTSO  
Q9R6Y9     :                                      LALRWQVVDHGIGEN----IFLGS--------LMITNNGLEPLGESGWALYFSSVRPPASVLPDSDPNGQYARQHIAAQNLSLENADDAKSGDYFVLKPVAGFAPIQPGESRTIEIVAQYWQMLKNDSPSGFHISYNNQAPQAVL------VDVMMDPSDPKQTKQAVNDNMPVQTSAIRFAENS--ATHMALPLKNRLVPQPHSV-VTPNDEFLTLMSQLTSISGAASLAKEATFLQTALRDILSGTFAINST-VQNGPNLIKLQLDPNLDTNQDNQPDASGYKLEVDAFSGITITGSDAQGVFYGIQTLRQMIPTTVYKTAKNSATLSDNAVLPASTILDAPRFEYRGMMLDVSRNFQSKETVFKLLDLMAFYKLNKFEINLANDEGWRLEIPGIPELTEFGAKRGYDLSESTMLHTFMGAANGFAPGDGIENKPTDETAANLGTAPSYQGFEIAQQNFLGKGWGYYTVNDFKEILQYAADRHIDVIIEYDFPAHARAAIKAMEHRYNK-YKDSDPVEANRFRLIDPLDQSQYYTPQFYT-DNFVNPALESTFTFLNHVVRETRAIYDAVPDATLTRLHGGGDELPHL----------------------GPNEWWAQSPAVDQNPATAGKT-DAE-LFDYFFLRWKQIVNQHGFD-MATWGDVLSHNGTGNV-SYGEIYPVFWNNVWGWGNEHQAYKFANQGHKVVLAHATNLYLDLAYNKHPDEIGYHWAG-YTDTKKAFEYRPFNIYANAER--DKLGNP--VPWDPKWVLLSEAGKQNVQGIQAQLFGENQKSPEILDYMTFPKLLGAAERAW-----VQDMPA----QGAAT----TEA----WHTFTNTLGQYALPLLDYYQVVDINAQIPQQVGVNYRIPLPGGAIEGGKLIVNTRFVGMATEYSVDQGVTWHRYEGPVTLTASSKVQLRTVSDSGK  Q9R6Y9  
Q9KUB0     :                                                                                                                                                                                                                                                                                               GHYQLNIEAQGIKIEAGSHSGFMHASATLLQLAQAHQGSLRFPLVNIVDAPRFKYRGMMLDCARHFHSLEQVKRVINQLAHYKFNVFHWHLTDDEGWRIEIKRLPQLTDIGAWRGMD----EVLEPQYSLLTERHGGFYTQDEIRAVIEYASDRGITVIPEIDVPGHSRAAIKALPA-----------------WLVDEEDCSQYRSIQYYN-DNVLSPALPGTYQFLDIVLEEVAALF-----PSQFIHIGADEVPH-----------------GV---------WVDSPKCQALMQEQGYTDPKELQGHLLRYAEKKLKSLG-KRMVGWEEAHHGDKVSK------------DTVIYSWLSEKAALDCAKQGFDVILQPGQFTYLDIVQDYAPEEPGVDWAGVTPLER-AYGYEPLADVPAN----------------DPLRKRILGIQCALWCELINNSERMEYMLYPRLTALAEGGW------------------------TEKSQRDWLDYLARL-KGHLPLLDKQKIPYRAP  Q9KUB0  
HEX1_VIBFU :                                                                                                                                                                                                                                                                                               GAYLLSVDRKPIRLEASSHIGFVHASATLLQLVRPDGDNLLVPHIVIKDAPRFKYRGMMLDCARHFHPLERVKRLINQLAHYKFNTFHWHLTDDEGWRIEIKSLPQLTDIGAWRGVD----EVLEPQYSLLTEKHGGFYTQEEIREVIAYAAERGITVIPEIDIPGHSRAAIKALPE-----------------WLFDEDDQSQYRSIQYYN-DNVLSPALPGTYRFLDCVLEEVAALF-----PSHFIHIGADEV--------------------------PDGVWVNSPKCQALMAEEGYTDAKELQGHLLRYAEKKLKSLG-KRMVGWEEAQHGDKVSK------------DTVIYSWLSEQAALNCARQGFDVILQPGQFTYLDIAQDYAPEEPGVDWAGVTPLER-AYRYEPLVEVPEH----------------DPLRKRILGIQCALWCELVNNQDRMDYMIYPRLTALA  HEX1_VIBFU  
Q60081     :                                                                                                                                                                                                                                                                                       FKGNPTLDEGAYKLKVAEESIKIEAGSSSGFTHACATLLQLIKVGDQPASMEVVCCSIKDRPRFRYRGMMLDCARHFHSVEQVKRLINQLAHYKFNTFHWHLTDDEGWRIEIKSLPQLTDIGAWR--GLDETN--EPQYSHLAERLRRFLHSRRHQRRGCLCFETRHHCYPEIDVPGHCRAAIKSL-----------------PHLLVEAEDTTEYRSIQHYN-DNVINPALPGSYEFIDKVLEEVSRCSL--------------------------------PLMFISVRISTNGVWSKSPACQALMEQLGYSDYKELQGHFLRHAEDKLRKLG-KRMLGWEEAQHGDKVSK------------DTVIYSWLSEEAALNCARQGFDVVLQPAQTTYLDMTQDYAPEEPGVDWANPLPLE-KAYNYEP-----LAEVPAD----------DPIRKRIWGIQTALWCEIINNQSRMDYMVFPRLTAMAEACW------------------------TDKQHRDWTDYLSRL-KGHLPLLDLQGVNYR  Q60081  
HEXA_PORGI :                                                                                                                                                                                                                         IIPLPMQLTESDDSFEVDDKTTICVSAEELKPIAKLLADKLRASADLSLQIEIGEEPSGNAIYIGVDTALPLKEEGYMLRSDKRGVSIIGKSAHGAFYGMQTLLQLLPAEVESSNEVLLPMTVPGVEIKDEPAFGYRGFMLDVCRHFLSVEDIKKHIDIMAMFKINRFHWHLTEDQAWRIEIKKYPRLTEVGSTRTE------------GDGTQ-YSGFYTQEQVRDIVQYASDHFITVIPMIEMPGHAMAAL----AAYPQFRCFPREFKPRIIWGVE---------------QDVYCAGKDSVFRFISDVIDEVAPLF-----PGTYFHIGGDECPKDR--------------------------WKACSLCQKRMRDNGLKDEHELQSYFIKQAEKVLQKHG-KRLIGWDEILEGGLAPSATVMS-----------WRGEDGGIAAANMNHDVIMTPGSGGLYLDH-YQGDPTVEPVAIG-GYAPLEQVYAYNP--LPKELPADKHR--------------YVLGAQANLWAEYLYTSERYDYQAYPRLLAVAELTW------------------------TPLAKKDFADFCRRL-DNACVRLDMHGINYHIPLP  HEXA_PORGI  
Q9L1V1     :                                                                                                                                                                                                                                                                                         GELADEG-YRLDIAPDGVRLTGGGPAGLFWGAQTLRQLLGPDAFRRAPLPGRRWRLPLGRIEDAPRFGWRGLMLDVSRHFMPKDGVLRQLDLMAAHKLNVLHFHLTDDQGWRIEIKRHPKLTGTGSWRSRTKFGHRA-SPLWEDKP--HGGYYTQEDIREIVAYAAARHITVLPEIDVPGHSQAAI----AAYPEL---------------GNTDVIDTTALSVWDTWGVSPNVLAP-TENTLRFYEGVFEEVLELF-----PSEFVHIGGDECPK--------------------DQ------WRASATAQARMAELGLADEDELQSWFIQHFDTWLAGRG-RRLIGWDEILEGGLAKGAAVSS-----------WRGYAGGIAAARAGHDVVMCPEQQVYLNFREDGGEDEPVPIAFVRTLED--VYRFEP--VP--AELTPEESGH------------VIGTQANLWTEVTENQERVDYQLFPRLAAFAEVAWSALPAPADRDYAAFERRMA--THYRRLDALGVAYRPPAGPRPWQRRPGVLGR  Q9L1V1  
Q9PF31     :                                                                                                                                                                                                                                                                                                                DGAGLFYGTITAWQLLTADSNQGPTEIPTVTIHDWPRFSWRGQLLDVARHFHDVDTVKHVIDAMAQHKLNVLHLHLTDDQGWRIEIKRYPKLTTIGAER---------IPPGAGRHGTPERYGGFYTQDQIRELVAYATERQITILPEIDMPGHAQAAVAAYP------------------DIIGVTGTTPPVSVD-WGVNPYLFDTATPSLDFIGNVLDEVLTLF-----PSPYIHIGGDEA--------------------VKDQ------WEASHTIRAQMRRLGVKDTHAMQGWFNTQLSQYLTTHG-RRLIGWDEIIQSGLADNAAVMS-----------WRGVDGAITAAQQGHDVVLAPAGWMYLDNLQTERSDEPNGRLAT--LPLSRVYALDPIPKELTPDQAIH----------------ILGLQSALWSEYIPSRWHIDHALFPRLAAVAEVAW  Q9PF31  
Q9ZH39     :                                                                                                                                                                                                                                                                        KTSGFPATAATRKNDMQSGIVLQIDSTNFSQDESYRIEVSRQQARLIGASKAGLFYAVETFKQLFDHSFFANAPVNQSQWVIPTVQISDQPRFAYRGMHLDVSRHFFDIEFIKNYIDWLAAHKFNVFQWHLTDDQGWRIEIKKYPKLTGVGARRSQTVVGHTYDYQPLFDGKTV-SGFYSQAQIKEVIEYAKARHIEVIPEIDIPGHSTALLAAYPEFGCKNQTLAVE---GNFGIFEPV----------------LCP-TEQTFAFLKNVYSEVAALF-----PSQYIHIGGDEVIKTQ--------------------------WLESAFVKQLMTEQGLSSGEQVQSYFIKRVSQIIKQLD-KKMIGWDEILEGGLAQDALVTS-----------WRGEEGGIKAAKLGHNVIMSPYQYIYFDAYQSESSEEPKAIHGLTRL---KQVYHYEP--IPK--ELTKDQQAL------------VLGAQGALWTEYIKTPRHAEYMLFPRLAALSEVLWSK---QKDWQA  Q9ZH39  
CAC34802   :                                                                                                                                                                                                                                                                                        KGSYGGEG-YRLESGRSGVTITARGPAGLFHGVQTLRQLLPPAVEKDSVQPGPWLVAGGTIEDTPRYGWRGAMLDVSRHFFTVDEVKRYIDQLALYKINKLHLHLSDDQGWRIAIDSWPNLAAYGGS------------TEVGGTP---GGFYTKDEYKEIVRYASSRFLEVVPEIDMPGHTNAALAS----YAELNCDG---------VAPPLYTG--------IRVGFSSLCVGKDITYDFVDDVVREIAEL-----TPGRYFHIGGDEGHSTPHADYVAFMDRVQP-----------------------VVAKYGKTVIGWHQLTSANPAEGALAQYWGVDATGA-------AEKARVAAA----------------------AQNGTGLILSPADRVYLDMKYDRN-TQLGLSW-AGYVEVQRSYDWDPGAYLPGAPESAIR-----------------GVEAPLWTETIENSAHIEHMAFPRLPGVAELGWSPA  CAC34802  
Q9L068     :                                                                                                                                                                                                                                                                                                 YRLDSGREGVTITARKAAGLFHGVQTLRQLLPAAVEKDSAQPGPWLVAGGTIEDTPRYAWRSAMLDVSRHFFSVDEVKRYIDRVALYKYNKLHLHISDDQGWRLAIDSWPRLATYGGS------------TEVGGGP---GGHYTKADYEEIVRYAASRHLEVVPEIDMPGHTNAALAS----YAELNCDG---------VAPPLYTG--TKVGF----STLCVDKDVTYDFVDDVLGELAAL-----TPGRYLHIGGDEAHS-------TPQA--------------DFVAFMKRVQPIVAKYGKTVVGWHQLAGAEPVEGALVQYWGLDR-------TSDAEKAQVAAAARNGTG----------------------LILSPADRTYLDMKY-TKDTPLGLSW-AGYVEVRRSYDWDPAAYLPGA-----------------PAEAVRGVEAPLWTETLSDPDQLDFMAFPRLPGVAELGWSPA  Q9L068  
O85361     :                                                                                                                                                                                                                                                                                                 YRLDSGPAGVTITARKAAGLFHGVQTLRQLLPPAVEKDSAQPGPWLVAGGTIEDTPRYAWRSAMLDVSRHFFGVDEVKRYIDRVARYKYNKLHLHLSDDQGWRIAIDSWPRLATYGGS------------TEVGGGP---GGYYTKAEYKEIVRYAASRHLEVVPEIDMPGHTNAALAS----YAELNCDG---------VAPPLYTG--TKVGF----SSLCVDKDVTYDFVDDVIGELAAL-----TPGRYLHIGGDEAHS-------TPKA--------------DFVAFMKRVQPIVAKYGKTVVGWHQLAGAEPVEGALVQYWGLDR-------TGDAEKAE----------------------VAEAARNGTGLILSPADRTYLDMKY-TKDTPLGLSW-AGYVEVQRSYDWDPAGYLPGA-----------------PADAVRGVEAPLWTETLSDPDQLDYMAFPRLPGVAELGWSPA  O85361  
Q9RHV6     :                                                                                                                                                                                                                                                                                                                  AGLFHGVQTLRQLLPPAVEKRTPQPGPWLVAGGTVEDRPRYAYRGAMLDVARHFLTVEQVKRYIDEIALYKFNTLRLHLSDDQGWRIAIDSWPRLATYGGS------------TQVGGGP---GGYYTKDDYREIVRYAASRYLEVVPEIDTPGHTNAALAS----YAELNCDG---------VAPPLYTG--TSVGF----SSLCVDKDITYTFLDDVIREVAAL-----TPGRYLHIGGDEAHSTSHEDYVTFMDRAQPIVATYGKTVIG-------W--HQLTATTPAEGA------LVQYWG------------------TDSTSDSEKEQVARAARNGTG----------------------VILSPADRIYVDMKY--TPDTPLGKSWAGYVEVQR----------------SYDWDPGSY--LPGVPASAVKGVEAALWTETLSTSDELDYMAFPRLPGAAELGWSPA  Q9RHV6  
Q9L448     :                                                                                                                                                                                                                                                                                         GAQLQAEAYTLSVDALTGAKITAATDDGIFNGVQTLRQLFPGIHCVQNQGQRHLDGS----CVEISDAPRFDKRGMMLDVAREFKNPDEVKAIIDSLASYKISTLHMHLADDQGWRIEITNEGKVAGDDIDYNQLTEISGKGGMTQFNRTYM--------DLLGNTGFYTQAEYKDLVAYAADRHIEIIPEIDVPGHTSAILHAI----PQLNTAGTKPNVDEWGVVPEDGTGNVGT-------STLDVAAPQTWTFLEHVFGQIAEMTTS-----EYIHIGGDES  Q9L448  
Q9L448     :                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               DKGAKLMVSNGSTAYLDMKYNAKTPI-GLTWAG-MGDFPKYYDWNP--------AAVVKDGT-----TNLPDSAILGVEAPQWSETIRGGKQTEFMVFPRVISFAEVGWTPQAKRNVSDFKVRMASMGSRLLAADTNFYDGNQAKWTPAMAGLPVAVSPGKSLKLDVG----QLAAPGTKASA  Q9L448  
Q9RK76     :                                                                                                                                                                                                                         LVPRPRRLSARSGRFRLDRTTRLRVTPGAGPAAVLLRTLLA------PATGLPLDSAAD-GAFVLALDPALTGLGDEGYGLTVSPQGVLLRAARPAGLLRGVQTVRQLLPYEALSGQPVRGVPWELPAVEITDVPRHAWRGSMLDVARHFQPVSYLQRYVDLLALHKLNVFHLHLTDDQGWRMPVAAHPRLTEVGGRRAESMVGPA--------GSDRFDGVPHGGSYTRAELRGLVAYAAERGVSVLPETGVPGHVRAAL----AAYPEL------------------GTDPARRLDVWTHWGVCENVLGTGENVLDFFRTVLDEVMDVF-----PSPYVHIGGDEVPTTEW---------------------ELSPAARARAA----REGLAGPRALHPWFIARLAEHLVRAG--RRPVVW------AESGVALPLDCTVMSWRDPAH------ARAAALRGHQVVHADHRATYFDYPRGAGPGEPPAQPGV-VVDLRAVHEVDLAPPT-PQAASR-------------------VLGAQGQLWTEFVRTPEHIEYLTFPRLCALAERVWDGTSGWRDFTA  Q9RK76  
Q9HGI3     :                                                                                                                                                                                                                                                       PSASAAATRSKRANVPIQF----VDVDVEDWDADLQHGVDESYTLDAKAGSDAIDITAKTVWGALHAFTTLQQLVISDGNGGLILEQPVHIKDAPLYPYRGLMVDTGRNFISVRKLHEQLDGMALSKLNVLHWHLDDTQSWPVHIDAYPEMT----KDAYSARET-----------------YSHDDLRNVVAYARARGIRVIPEIDMPAHSASGWQQVD---PDIVACANSWWSNDNWPLHTAVQPNPGQLDIINPKTY---------EVVQDVYEELSSIFTD-----DWFHVGGDEIQPNCYNFSTY-----------VTEWFQEDPSRTYNDLMQHWVDKA-------VPIFRSVSDSR--------RLVMWEDVVLNTEHADDVPTDIV-MQSWN----NGLENINKLTERGYDVIVSSADFMYLDCGRGGYVTNDDRYNEQTNPDPDTPSFNYGGIGGSWCGPYKTWQRIYNY-------------DFTLNLTNAQAKH----VIGATAPLWSE-QVDDVNISNLFWPRAAALAELVW  Q9HGI3  
Q9GPG8     :                                                                                                                                                                                                                              IQITKQGKSDDLLKAAADRFKTLVSSS---VPKGFSAKAAGKSVTVYLVNENPYIREF--SLDMDESYELYISSTSSDKVKATIPGNSFFGVRNGLETLFQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIDSIKRTIDAMAAVKLNTFHWHITDSQSFPLVLQKSPNFSKLGA-----YSPTK---------------VYTKQDIREVVEYGLERGVRVLPEFDAPAH-----VGEGWQDTGLTVCFKAEPWTKFCVEPPC--------------GQLNPTKEEHYDYLVDIYVEMA----EAFESTDMFHMGGDEV--------------------------SERCWNSSEEIQNFMIQNRWNLDKSSFLKLWNYFQKNAQDRAYKAFGKRLPLILWTSRLTDYTHVEKFLDKDEYIIQVWTT---GADPQIQGLLQKGYRLIMSNYDALYFDCGFGAWVGS-GNNWCSPYIGGQKVYGNSPAVMALSYREQI------------------LGGEVALWSE--QSDPATLDGRLWPRAAAFAERMWAEPSTAWQDADHRMLHVRERLVRMGIQAESLEPDW  Q9GPG8  
Q9KI44     :                                                                                                                                                                                                                                                                                         GGPGADETYQVVVRAGRVEVRSPSVAGLVHGVVTLRQLATVDEGSVRIPAVRIQDAPRFAWRGLSIDVARHFFGVEDLKGVIGLMAHYKLNVLHLHLTDEQGWRLHVPSRPKLTELSSDSAGGGRPRRLLHAGGLRRAHRVRRGAAASAWSR-------------------EIDVPGHVNAA----------LHAYGELTPSGE-----PTDVYDGIEVGF----SRLHADLPATRPFLEAVFTDVAAM--TAGEHV---HIGGDEVLTM-----------------------EPEEYAR----------------------FVALAAQVVRAAG-KEVVGWQ------EIAHTPLEPGTVVQYWDTRV--DPEPFVRAAREGARLLMSPGSKAYLDMKYDAS-FPLGLEWAGRI-EVRDAYDWEPTTLIEGL-----------------PAESVIGVEAAVWTETLRTLDDLTTMLLPRLAAVAEVAW  Q9KI44  
HEXC_BOMMO :                                                                                                                                                                                                                                                                                                SYELYISSTSSDKVNATIRGNSFFGVRNGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIDSIKRTIDAMAAVKLNTFHWHITDSQSFPLVLQKRPNLSKLGA-----YSPTK---------------VYTKQDIREVVEYGLERGVRVLPEFDAPAH-----VGEGWQDTGLTVCFKAEPWTKFCVEPPC--------------GQLNPTKEELYDYLEDIYVEMA----EAFESTDMFHMGGDEV--------------------------SERCWNSSEEIQNFMIQNRWNLDKSSFLKLWNYFQKNAQDRAYKAFGKRLPLILWTSTLTDYTHVEKFLDKDEYIIQVWTT---GADPQIQGLLQKGYRLIMSNYDALYFDCGFGAWVGS-GNNWCSPYIGGQKVYGNSPAVMALSYRDQI------------------LGGEVALWSE--QSDPATLDGRLWPRAAAFAERMW  HEXC_BOMMO  
Q9VZE3     :                                                                                                                                                                                                                                                                              INTPDEPTPARLTLDTDESYTLDIDTDASGHVLANITASNFFGARHGLETLAQLIVYDDIRREVQVTANATINDAPVYKWRGLLLDTSRNYYSVKSIKRTLEGMALVKLNTFHWHITDSHSFPLEVKKRPELHKLGA---------------YSQRQ-----VYTRRDVAEVVEYGRVRGIRVMPEFDAPAH-----VGEGWQHKNMTACFNAQPWKSFCVEPPC--------------GQLDPTVNEMYDVLEDIYGTMFDQFNP-----DIFHMGGDEVST--------------------------SCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDKVANGTHTPIILWTSGLTEEPFIDEYLNPERYIIQIWTT---GVDPKVKKILERGYKIIVSNYDALYLDCG-GAGWVTDGNNWCSPYIGWQKVY--------DNSLKSIAGDYEHH----------VLGAEGAIWSE-QIDEHTLDNRFWPRASALAERLWSNPAEGWRQ  Q9VZE3  
P78738     :                                                                                                                                                                                                                                                                                             VDESYSLTISKNGQVNISAKSSTGVLHALETFSQLFYKHSAGPFYYTTQAPVSITDAPKYPHRGIMLDLARNYQTIDDIKRTIDAMSWNKLNRLHLHITDSQSWPLVIPSLPKLSQAGAYH-----------------PSL---VYTPADLAGIFQYGVARGVEVITEIDMPGH----IGVIELAYSDLIVAYEE  P78738  
Q9URR8     :                                                                                                                                                                                                                                                                                                                   GVLQAFTTLQQIIISDGKGGLIIEQPVKIKDAPLYPHRGIMIDTGRNFITVRKLLEQIDGMALSKLNVLHWHLDDSQSWPMQMSSYPEMTK-----------------------DAYSPREIYTEHDMRRVIAYARARGVRVIPEVDMPAHSASGWQQVD---PEIVACAESWWSNDV-------WAEHTAVQ--PNPGQLDIIYPKTYEVVNNVYQELSRIFSD-----NLFHVGADEIQ-----------------PNCYNYSTHITKWFAEDPSRT---------YNDLAQYWVDHSMPIFRSVGDHRRLMMWED-IAIATESAHDVPKDVIMQTWNS--GEGEGNIKKLTSAGYDVVVSTSDFLYLDC-------GRGGY----------VTNDARYNVQSNTDGGVNFNYGGDGGSWCAPY-KTWQRIYDYDFLTNLTSSEAKHIIGAEAPLWSE-QVDDVTVSSVFWPRAAALGELVW  Q9URR8  
HEX1_CANAL :                                                                                                                                                                                                                                                                          NGKNIKTSLVHIQVDDATVDLQLGVNESYTLKINTDGINIHAATTWGALHGLVSLQQLIIHTSEDKYVVPSSVTISDFPNFKHRGLMIDSGRNFLTVDSILEQIDIMALSKMNSLHWHLADSQSWPVALESYPHMIK-----------------------DAYSNDEVYSKNDLKYIVDYARARGVRVIPEIDMPGHARA  HEX1_CANAL  
HEX1_CANAL :                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    WHEISGVKNLTSRGYDVVVSSSDFLYLDCGNAGWVTNDPRYVETPENVDFNTGQGGSWCGPYKSYQRIYNF--DFTANLTET----EKNH-----------VLGREAALWSE-QVDSTVLTTKIWPRTAALAELTWSGNKDSNGHHRGYE  HEX1_CANAL  
HEXA_DICDI :                                                                                                                                                                                                                         VVPYPQQVSIGTCVIPVAPGSILIESNIESATFSVSMDRYTNLFFPFSNESEPSSNESFLLSVTIYSDDETLQLGIDESYSLSIEQGSYQLKATNIYGAMRGLETFKQLIVYNELENSYSIVCVSISDSPRYPWRGFMVDSARHYIPKNMILHMIDSLGFSKFNTLHWHMVDAVAFPVESTTYPDLT---------------------KGAFSPSATFSHDDIQEVVAYAKTYGIRVIPEFDIPGHAAAWGIG----YPELVATCPDYAANVNNI--PLDISNPATF-----------------TFIQNLFTEIAPLFID-----NYFHTGGDE---LVTGCWLEDPA----------------------IANWMTKMG--FSTTDAFQYFENNLDVTMKS--INRTKITWNDPIDYGVQLNPETLVQV---------WSSGSDLQGIVNSGYKALVSFAWYL-----DKQNPDNNIHYEWQDTWQD---FYAADPTNNISTNAENII-------------------GGEATMWAE-QINQVNWDVRVWPRAIGIAERLW  HEXA_DICDI  
O18795     :                                                                                                                                                                                                                                                                                                                   GVLRGLETFSQLIYQDSYGTFTVNESDIIDSPRFPHRGILIDTARHFLPVKSILKTLDAMAFNKFNVLHWHIVDDQSFPYQSVTFPELSNKGS---YSLSHV-----------------YTPNDVHTVIEYARLRGIRVIPEFDSPGHTQ--------------SWGKGQK----DLLTPCYNEHKQSGTF----GPINPILNSTYNFLSQFFKEVSMVF-----PDHFVHLGGDEVE  O18795  
HEXA_CAEEL :                                                                                                                                                                                                                                                                                              SEEYLLRVSLTEAVINAQTVWGALRAMESLSHLVFYDHKSQEYQIRTVEIFDKPRFPVRGIMIDSSRHFLSVNVIKRQLEIMSMNKLNVLHWHLVDSESFPYTSVKFPELHGVGAYS-----------PRH---------VYSREDIADVIAFARLRGIRVIPEFDLPGHTS----SWRGRKGFLTECFDEKGVETFLPNLVDPMNEANFD--------------------FISEFLEEVTETF-----PDQFLHLGGDEVSDY-----------------IVECWERNK-----KIRKFMEEKGFGNDTVLLENYFFEKLYKIVENLKLKRKPIFWQEVFDNNIPDPNAV----IHIWKGNTHEEIYEQVKNITSQNFPVIVSACWYLNYIKY----GADWRDEIRGTAPSNSRYYYC----------------DPTNFNGTVAQKELVWGGI----AAIWGELV-DNTNIEARLWPRASAAAERLWSPA  HEXA_CAEEL  
HEXB_FELCA :                                                                                                                                                                                                                                                                                                                   GVLRGLETFSQLIYQDSYGTFTVNESDIIDSPRFPHRGILIDTARHFLPVKSILKTLDAMAFNKFNVLHWHIVDDQSFPYQSVTFPELSNKGS---YSLSHV-----------------YTPNDVHTVIEYARLRGIRVIPEFDSPGHTQ--------------SWGKGQK----DLLTPCYNEHKQSGTF----GPINPILNSTYNFLSQFFKEVSMVF-----PDHFVHLGGDEVE  HEXB_FELCA  
Q9W3C4     :                                                                                                                                                                                                                                                                                                SYALVVRTTETATFVDIQATTVYGARHAFETLSNLVTGSLSNGLLMVTTANITDRPAFSHRGVLLDTARNFVPLKFIRSTLDAMAASKLNVLHWHVVDTHSFPLEITRVPEMQRYG---AYSSSQT-----------------YSRQDALNLVKYARLRGIRILIEIDGPSHAGNGWQWGPAAGLGNMSVCLNQSPWRRFCVQPPC--------------GQLNPLNDHMYAVLKEIFEDVA----EVGAPEETLHMGGDE  Q9W3C4  
HEXB_MOUSE :                                                                                                                                                                                                                                                                                                                   GALRGLETFSQLVYQDSFGTFTINESSIADSPRFPHRGILIDTSRHFLPVKTILKTLDAMAFNKFNVLHWHIVDDQSFPYQSTTFPELSNKGS---YSLSHV-----------------YTPNDVRMVLEYARLRGIRVIPEFDTPGHTQ--------------SWGKGQK----NLLTPCYNQKTKTQVF----GPVDPTVNTTYAFFNTFFKEISSVF-----PDQFIHLGGDEV--------------------------EFQCWASNPNIQGFMKRKGFGSDFRRLESFYIKKILEIISSLKKNSI-VWQEVFDD----KVELQPGTVVEVWKSEHYS--YELKQVTGSGFPAILSAPWYLDL---ISYGQDWKNYY---------KVEPLNFEGSEKQKQLVIGGEACLWGEFVDATNLTPRLWPRASAVGERLWSPKTVTDLENAY  HEXB_MOUSE  
P78739     :                                                                                                                                                                                                                                                                                            AVNESYALDVDAKGHASLTAPSSTGILRGLETFSQLFFKHSSGTAWYTQLAPVSIRDEPKYPHRGLLLDVSRHWFEVSDIERTIDALAMNKMNVLHLHATDTQSWPLEIPSLPLLAEKGA---------------YHKGLS-----YSPSDLASIQEYGVHRGVQVIVEIDMPGH  P78739  
P87258     :                                                                                                                                                                                                                                                                     IAIQQTGKDTATTFKPR----AGDVDESYSLTVSKNGQVNISAKTSTGILHALETFSQLFYQHSAGHYFYTTQVPVSIQDSPNYPHRGVMLDLARTYQTVADIKRTIDAMSWNKLNRLHLHITDSQSWPLVIPSLPKLSQEGAYH-----------------PSL---VYSPADLAGIFQYGIDRGVEVITEIDMPGH----IGVVELAYSDLIVAYQEMPYQYYCAEPPCGAFSFNDSKVYD--------------FVDKLFDDLL---PRVTPYSSYFHTGGDEL---------------NANDSMIDPRYKSN---SSDVLQPLLQK------------------FISHAHSKIRAQ----GLSPLVCEEMVTTWNLTLGS-DTVVQSWLGGDAVKNLAESGYKVIDTDYNFYYLDCGRGQWVNFP---NGDSFNTYYPFSDWCAPTKNWRLIYSHDPAKGVSKA-----------NAKN------VLGGELAIWSE-MIDGSNMDNIIWPRGSAAGEVWW  P87258  
Q9SYK0     :                                                                                                                                                                                                                                                                                             VDESYKLSIPIGSFSAHLLAHSAWGAMRGLETFSQMIWGTSPDLCLPVGIYIQDSPLFGHRGVLLDTSRNYYGVDDIMRTIKAMSANKLNVFHWHITDSQSFPLVLPSEPSLAAKG-----------------SLGPDM---VYTPEDVSKIVQYGFEHGVRVLPEIDTPGHTGSWGEAYPEIVTCANMF--WWPAGKSWEE---RLASEPGTGQ------------LNPLSPKTYEVVKNVIQDIVNQFPES-----FFHGGGDE---VIPGCWKTDPAINSFLSSGGTLSQLLEKYINSTLPYIVSQNRTVVYWEDVLLDAQ-----IKADPSVLPKEHTI--LQTWNNG---PENTKRIVAA------------------------GYRVIVSSSEFYYLDCGHGGFLGNDSIYDQKESGGGSWCAPFKTWQSIYNYDIADGLLNEEERKL-----------------VLGGEVALWSE-QADSTVLDSRLWPRASALAESLW  Q9SYK0  
HEXA_HUMAN :                                                                                                                                                                                                                                                                                                 YTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKG---------------SYNPVTHIY----TAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG------------------LLTPCYSGSEPSGTF----GPVNPSLNNTYEFMSTFFLEVSSVF-----PDFYLHLGGDE-------VDFTCWKSNPE-------------------IQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYV-VWQEVFDNKVKIQP-----------DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAY  HEXA_HUMAN  
HEXA_MOUSE :                                                                                                                                                                                                                                                                                                 YTLTINDDQCLLASETVWGALRGLETFSQLVWKSAEGTFFINKTKIKDFPRFPHRGVLLDTSRHYLPLSSILDTLDVMAYNKFNVFHWHLVDDSSFPYESFTFPELTRKG-----SFNPVTHI--------------YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGAPG------------------LLTPCYSGSHLSGTF----GPVNPSLNSTYDFMSTLFLEISSVF-----PDFYLHLGGDEV--------------------------DFTCWKSNPNIQAFMKKKGFTDFKQLESFYIQTLLDIVSDYDKGYV-VWQEVFDNKVKVRPDTIIQVWREEMPVEY---MLEMQDITRAGFRALLSAPWY--------LNRVKYGPDWKDMYKVEPLAFHGTPEQKALVIGGEACMWGEYVDSTNLVPRLWPRAGAVAERLWSSNLTTN  HEXA_MOUSE  
AAH01138   :                                                                                                                                                                                                                                                                                                                   GALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKG---------------SYNPVTHIY----TAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG------------------LLTPCYSGSEPSGTF----GPVNPSLNNTYEFMSTFFLEVSSVF-----PDFYLHLGGDE-------VDFTCWKSNPE-------------------IQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYV-VWQEVFDNKVKIQP-----------DTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAY  AAH01138  
HEXB_PIG   :                                                                                                                                                                                                                                                                                                SYVLHVKGPEALLRANTVWGALRGLETFSQLIYQDSYGTFTVNESEIIDFPRFPHRGILIDTGRHFLSVKTIFKTLDAMAFNKFNVLHWHIVDDQSFPYQSINFGVLSSKGS---YSLSHV-----------------YTPNDVRMVIEYARIRGIRVMPEFDTPGHSR--------------SWGKGQK----DLLTPCYRKQVLSGTF----GPINPILNTTYNFLSKFFKEISTVF-----PDEFIHIGGDE  HEXB_PIG  
HEXB_HUMAN :                                                                                                                                                                                                                                                                                                                   GALRGLETFSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGS---YSLSHV-----------------YTPNDVRMVIEYARLRGIRVLPEFDTPGHTL--------------SWGKGQK----DLLTPCYSRQNKLDSF----GPINPTLNTTYSFLTTFFKEISEVF-----PDQFIHLGGDEV--------------------------EFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSI-VWQEVFDD----KAKLAPGTIVEVWKDSAY---PEELSRVTASGFPVILSAPWYLDL---ISYGQDWRKYY---------KVEPLDFGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAY  HEXB_HUMAN  
Q9V6C8     :                                                                                                                                                                                                                                                                                                         QVEIIANSYFGARHGLSTLQQLIWFDDEDHLLHTYANSKVKDAPKFRYRGLMLDTSRHFFSVESIKRTIVGMGLAKMNRFHWHLTDAQSFPYISRYYPELAVHG---AYSESET-----------------YSEQDVREVAEFAKIYGVQVIPEIDAPAHA  Q9V6C8  
P90609     :                                                                                                                                                                                                                                                                                                                                                   PWRGVMLDTCRRFFDADSIKRLLYGMAQQKLNKFHWHINDDSGWRLEVKKYPNLI-IKGSSC  P90609  
Q9M3C5     :                                                                                                                                                                                                                                                                                           LGVDESYTLMVSKKNEQSIVGAATIEANTVYGALRGLETFSQLCAFDYITKSVQIYKAPWYIQDKPRFGYRGLLIDTSRHYLPIDVIKQIIESMSFAKLNVLHWHIVDEQSFPLETPTYPNLWKGAYSRWERYTVEDASEIVRFAKMRDFY--------FNDLLLMVERLITGINVMAEVDVPGHAES  Q9M3C5