About me
This website covers my activity as a PhD student between 2006 and 2009 at the MRC Laboratory of Molecular Biology (LMB) and Cambridge University.
At the LMB I was member of the Systems Biology and Theoretical and Computational Biology groups. My advisor was M. Madan Babu.
Professional affiliations
Past affiliations:
University of California San Francisco,
Wellcome Trust Sanger Institute,
American Express Europe,
Sussex University,
RMA International,
BGRG VIII Albertgasse.
PhD dissertation
The role of small molecules in cell regulation.
[
Summary |
Chapter 0 |
Chapter 1 |
Chapter 2 |
Chapter 3 |
Chapter 4 |
Chapter 5 |
Chapter 6 |
Appendix
]
Publications
most recent on top
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Laura Kapitzky et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action,
Molecular Systems Biology 6, 451.
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Arthur Wuster et al. (2010) Spial: Analysis of subtype-specific features in multiple sequence alignments of proteins,
Bioinformatics 26, 2906.
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Arthur Wuster and M. Madan Babu (2009) Transcriptional control of the quorum sensing response in yeast,
Molecular BioSystems 6, 134.
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Raja Jothi et al. (2009) Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture,
Molecular Systems Biology 5, 294.
[ PDF ]
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Arthur Wuster and M. Madan Babu (2008) Bringing together small molecules and genomics for biotechnology,
Trends in Biotechnology 26, 252.
[ PDF ]
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Arthur Wuster (2008) Networking with drugs,
Molecular BioSystems 4, 14.
[ PDF ]
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Arthur Wuster and M. Madan Babu (2008) Conservation and evolutionary dynamics of the agr cell-to-cell communication system across firmicutes,
Journal of Bacteriology 190, 743.
[ PDF ]
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Arthur Wuster and M. Madan Babu (2007) Chemical Molecules that Regulate Transcription and Facilitate Cell-to-Cell Communication,
Wiley Encyclopaedia of Chemical Biology.
[ PDF ]
Wer wagt, gewinnt
This essay (in German) is about the need for risk-taking in science. It led to an invitation to the 39th St. Gallen Symposium.
Added 19 August 2009
Drawings from DNA
There are four nucleotides in DNA: adenine (A), cytosine (C), guanine (G), and thymine (T).
There are also four basic directions a line can go on a piece of paper: up, down, left, or right.
The pictures below are representations of DNA, where each of the four nucleotides makes the line go a step in one of the four directions.
[
human histone H1 |
human mtDNA |
human p53 |
Escherichia coli genome |
Mycoplasma genitalium genome
]
Red line: A makes the line go up, C down, G left, and T right.
Blue line: A makes the line go up, C left, G right, and T down.
Green line: A makes the line go up, C left, G down, and T right.
Added 19 March 2008
Food species whose genomes have been sequenced
If you like to know what you eat, this is for you:
A list of plant, animal and bacterial species that can be eaten and whose genomes have been sequenced or are about to be sequenced.
Recipes using only those species as ingredients would be very welcome!
Added 11 January 2008
Fighting the bacterial communication war
This essay is about the importance of research into quorum sensing.
It won a prize in the Wellcome Trust and New Scientist Essay Competition 2007.
Added 29 August 2007
RNAs from aaRNA to zygRNA
RNA abreviations are all the rage: tRNA, rRNA, siRNA.
Want to jump on the bandwagon but feel confused or intimidated?
Or just appreciate a good list?
Then this is for you.
The file is also available as a tab-delimited text document here.
Added 22 July 2007
Last update 7 Feb 2011