* Drosophila or C. elegans immunoglobulin proteins
* structural annotation
* homologous proteins in other metazoan organisms
One of the major questions in evolutionary structural genomics is how the differences in physiological complexity between organisms are reflected at the level of proteins and protein families. We characterised one of the largest protein families, the Immunoglobulin superfamily (IgSF), in Drosophila melanogaster (fly) and compared it to a similar set in Caenorhabditis elegans (worm) in order to investigate this question. We identified homology amongst these proteins according to similarity in sequence, domain architecture and function in order to exemplify the extent to which genes are conserved or specific across the two organisms.
Updates -- Files and Notes. (last change: Jan 04)
| Drosophila melanogaster | Immunoglobulin proteins used in this paper. |
| Caenorhabditis elegans | Immunoglobulin proteins used in this paper. |
| Drosophila melanogaster | proteins with Immunoglobulin domains assigned by SUPERFAMILY database. |
| Anopheles gambiae | proteins with Immunoglobulin domains assigned by SUPERFAMILY database. |
| Caenorhabditis elegans | proteins with Immunoglobulin domains assigned by SUPERFAMILY database. |
| Caenorhabditis briggsae | proteins with Immunoglobulin domains assigned by SUPERFAMILY database. |
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