- Insulin-like (56993)
nearly all-alpha
can be classified as disulfide-rich
- T-antigen specific domain-like (999807)
all-alpha zinc-binding domain; there are two zinc ion-binding siteswith a common CxCxxC motif but different fourth ligands
- E7 C-terminal domain-like (999801)
alpha+beta zinc-binding domain; beta(2)-alpha(2)
- E6 C-terminal domain-like (999793)
alpha+beta zinc-binding fold with topological similarity to the fold of lambda cro protein
- Zinc hairpin stack (999787)
stack of beta-hairpins; in the middle hairpins, there is HCxxCxxC motif, the first and the last residues of which contribute to the zinc-binding site on one side of hairpin, whereas the middle residues contribute to the zinc-binding site on the other side
- CHY zinc finger-like (999781)
trimetal-bound fold; integration of HIT/MYND-like and rubredoxin-like fingers
- Knottins (small inhibitors, toxins, lectins) (57015)
disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
- PMP inhibitors (57282)
disulfide-rich fold; all-beta: 3 antiparallel strands
- Midkine (57287)
disulfide-rich fold; all-beta: 3 antiparallel strands
- TSP-1 type 1 repeat (82894)
disulfide-rich fold; all-beta: 3 antiparallel strands
- Amb V allergen (57295)
disulfide-rich; alpha+beta: 3 antiparallel strands followed by a short alpha helix
- Snake toxin-like (57301)
disulfide-rich fold: nearly all-beta
- BPTI-like (57361)
disulfide-rich alpha+beta fold
- Defensin-like (57391)
Disulfide-rich fold, nearly all-beta
- Hairpin loop containing domain-like (57413)
alpha+beta fold with two crossing loops
- Neurotoxin III (ATX III) (57418)
disulfide-rich fold
- LDL receptor-like module (57423)
disulfide-rich calcium-binding fold
- Crambin-like (57428)
disulfide-rich alpha+beta fold
- Kringle-like (57439)
disulfide-rich fold; nearly all-beta
- Kazal-type serine protease inhibitors (100894)
- Plant proteinase inhibitors (100896)
disulfide-rich small alpha+beta fold; topological similarity to the Ovomucoid domain III
- Trefoil/Plexin domain-like (57491)
disulfide-rich fold; common core is alpha+beta with two conserved disulfides
- Necrosis inducing protein 1, NIP1 (103579)
disulfide-rich fold; all-beta; duplication: contains two structural repeats
- Cystine-knot cytokines (57500)
disulfide-rich fold; common core is all-beta
- Complement control module/SCR domain (57534)
disulfide-rich all-beta fold
- Crisp domain-like (57545)
disulfide-rich all-alpha fold
- Blood coagulation inhibitor (disintegrin) (57551)
small disulfide-rich
- Methylamine dehydrogenase, L chain (57560)
disulfide-rich; nearly all-beta
- Serine protease inhibitors (57566)
disulfide-rich; nearly all-beta
- TB module/8-cys domain (57580)
disulfide-rich; alpha+beta
- TNF receptor-like (57585)
duplication: consists of three similar disulfide-rich domains
- Heparin-binding domain from vascular endothelial growth factor (57592)
duplication: consists of two similar disulfide-rich domains, alpha+beta
- Antifungal protein (AGAFP) (57597)
disulfide-rich; all-beta: open barrel, 5 strands; OB-fold-like
- FnI-like domain (57602)
disulfide-rich, all-beta
- Thyroglobulin type-1 domain (57609)
disulfide-rich, alpha+beta
- Type X cellulose binding domain, CBDX (57614)
disulfide-rich, alpha+beta
- Cellulose docking domain, dockering (64570)
disulfide-rich, alpha+beta
- Carboxypeptidase inhibitor (57619)
disulfide-rich, alpha+beta
- Invertebrate chitin-binding proteins (57624)
disulfide-rich
- Pheromone ER-23 (69963)
disulfide-rich, all-alpha
- Mollusk pheromone (90182)
disulfide-rich; all-alpha
- Apical membrane antigen 1 (82909)
disulfide-rich, alpha+beta
- Somatomedin B domain (90187)
disulfide-rich
- Notch domain (90192)
disulfide-rich; all-alpha; calcium-binding
- Mini-collagen I, C-terminal domain (103588)
disulfide-rich
- Hormone receptor domain (111417)
disulfide-rich all-beta fold; contains beta sandwich of 5 strands
- Resistin (111422)
disulfide-rich six-stranded beta-sandwich; jelly-roll
- YAP1 redox domain (111429)
bipartite cysteine-rich all-alpha domain; a single helix in the N-terminal part (chain A) is linked by disulfides to the C-terminal part (chain B) [3-helical bundle of the RuvA C-terminal domain-like fold (scop_cf 46928)
- Tim10-like (144121)
alpha-hairpin crosslinked by two disulfides; assembles into a heterohexameric ring-like structure
- Cysteine zipper (144128)
string of helices that contain cysteines at almost every turn; folds upon itself and is crosslnked by multiple disulfides
- GLA-domain (57629)
Calcium ion-bound
- Cholecystokinin A receptor, N-domain (57641)
a few helical turns and a disulfide-crosslinked loop
- HIV-1 VPU cytoplasmic domain (57646)
a few helical turns assembled without a hydrophobic core?
- HIPIP (high potential iron protein) (57651)
folds around 4Fe-4S cluster
- Ferredoxin thioredoxin reductase (FTR), catalytic beta chain (57661)
folds around 4Fe-4S cluster
- C2H2 and C2HC zinc fingers (57666)
alpha+beta metal(zinc)-bound fold: beta-hairpin + alpha-helix
- Zn2/Cys6 DNA-binding domain (57700)
all-alpha dimetal(zinc)-bound fold
- Glucocorticoid receptor-like (DNA-binding domain) (57715)
alpha+beta metal(zinc)-bound fold
- SBT domain (103611)
consist of two different zn-binding subdomains, each subdomain resembles a distorted glucocorticoid receptor-like fold
- Retrovirus zinc finger-like domains (57755)
metal(zinc)-bound fold
- Rubredoxin-like (57769)
metal(zinc or iron)-bound fold; sequence contains two CX(n)C motifs, in most cases n = 2
- Ribosomal protein L36 (57839)
zinc-bound beta-ribbon motif
- Zinc-binding domain of translation initiation factor 2 beta (75688)
zinc-bound beta-ribbon motif
- WRKY DNA-binding domain (118289)
zinc-bound 4-stranded meander beta-sheet, distinct from the beta-ribbon motifs
- B-box zinc-binding domain (57844)
zinc-bound alpha+beta motif
- RING/U-box (57849)
dimetal(zinc)-bound alpha+beta motif; structurally diverse
- ArfGap/RecO-like zinc finger (57862)
zinc-bound alpha+beta motif
- Metallothionein (57867)
metal(iron)-bound fold
duplication: consists of clear structural/sequence repeats
- Zinc domain conserved in yeast copper-regulated transcription factors (57878)
metal(zinc)-bound alpha+beta fold
- Ada DNA repair protein, N-terminal domain (N-Ada 10) (57883)
metal(zinc)-bound alpha+beta fold
- Cysteine-rich domain (57888)
dimetal(zinc)-bound alpha+beta fold
- AN1-like Zinc finger (118309)
dimetal(zinc)-bound alpha+beta fold; partial similarity to the Cysteine-rich domain fold (scop_cf 57888)
- HIT/MYND zinc finger-like (144231)
dimetal(zinc)-bound alpha+beta fold; structural similarity to members of the Cysteine-rich domain fold (scop_cf 57888)
- Toxic hairpin (57006)
disulfide crosslinked alpha-helical hairpin
- FYVE/PHD zinc finger (57902)
dimetal(zinc)-bound alpha+beta fold
- Zn-binding domains of ADDBP (57916)
metal(zinc)-bound alpha+beta fold
- Inhibitor of apoptosis (IAP) repeat (57923)
metal(zinc)-bound alpha+beta fold
- CCCH zinc finger (90228)
metal(zinc)-bound alpha+beta fold
- Zinc finger domain of DNA polymerase-alpha (90233)
Zn-binding, all-alpha fold
- TAZ domain (57932)
all-alpha fold; Zn-binding sites are in the loops connecting helices
- Cysteine-rich DNA binding domain, (DM domain) (82926)
alpha-helical fold with two Zn-binding sites
- Coronavirus NSP10-like (144245)
binds two zinc ion per subunit; forms a dodecameric shell
- DnaJ/Hsp40 cysteine-rich domain (57937)
metal(zinc)-bound extended beta-hairpin fold
- HSP33 redox switch-like (118351)
alpha+beta zinc-binding domain; alpha(2)-beta(2)-alpha
- CCHHC domain (103636)
metal(zinc)-bound fold
- Sec-C motif (103641)
metal(zinc)-bound fold
- Viral leader polypeptide zinc finger (144250)
consists of small beta-hairpin with CxH motif and short helix with CxxC motif
- TSP type-3 repeat (103646)
metal(calcium)-bound fold
- Expressed protein At2g23090/F21P24.15 (118358)
not assigned; partly disordered
- Intrinsically disordered proteins (144255)
not a true fold