Lineage

Root
1. Class Alpha and beta proteins (a+b) [53931] (53931)
2. Fold DNA breaking-rejoining enzymes (56348)

core: alpha3-beta3-alpha4; one side of beta-sheet is exposed

3. Superfamily DNA breaking-rejoining enzymes (56349)

Superfamily

Family

Eukaryotic DNA topoisomerase I, catalytic core (56361)

Protein Children