Lineage

Root
1. Class Alpha and beta proteins (a+b) [53931] (53931)

Fold

Hect, E3 ligase catalytic domain (56203)

consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

Superfamily Children