core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
Superfamily
duplication: both domains have similar folds and functions most members of the family contain common C-terminal alpha+beta domain
Thioredoxin reductase (51950)
lacks the "interface" C-terminal alpha+beta domain