Lineage

Root
1. Class Alpha and beta proteins (a+b) [53931] (53931)
2. Fold Profilin-like (55769)

core: 2 alpha-helices and 5-stranded antiparallel sheet: order 21543; 3 layers: alpha/beta/alpha

Superfamily

Roadblock/LC7 domain (103196)

alpha-beta(2)-alpha-beta(3)-alpha; structurally most similar to the SNARE-like superfamily with a circular permutation of the terminal helices
Superfamily

Family Children